de Lima Ana Paula, Kitakawa Dárcio, Almeida Janete Dias, Brandão Adriana Aigotti Haberbeck, Anbinder Ana Lia
Department of Bioscience and Oral Diagnosis, School of Dentristy of São José dos Campos, UNESP-Univ Estadual Paulista, Avenida Francisco José Longo, 777, Jd, São Dimas, São José dos Campos CEP 12245-000, Brazil.
BMC Res Notes. 2012 Aug 23;5:455. doi: 10.1186/1756-0500-5-455.
Odontogenic tumors are lesions that are derived from remnants of the components of the developing tooth germ. The calcifying cystic odontogenic tumor or calcifying odontogenic cyst is a benign cystic neoplasm of odontogenic origin that is characterized by an ameloblastoma-like epithelium and ghost cells. Calcifying cystic odontogenic tumor may be centrally or peripherally located, and its ghost cells may exhibit calcification, as first described by Gorlin in 1962. Most peripheral calcifying cystic odontogenic tumors are located in the anterior gingiva of the mandible or maxilla.
Authors report a rare case of a peripheral calcifying cystic odontogenic tumor of the maxillary gingiva. A 39-year-old male patient presented with a fibrous mass on the attached buccal gingiva of the upper left cuspid teeth. It was 0.7-cm-diameter, painless and it was clinically diagnosed as a peripheral ossifying fibroma. After an excisional biopsy, the diagnosis was peripheric calcifying cystic odontogenic tumor. The patient was monitored for five years following the excision, and no recurrence was detected.
All biopsy material must be sent for histological examination. If the histological examination of gingival lesions with innocuous appearance is not performed, the frequency of peripheral calcifying cystic odontogenic tumor and other peripheral odontogenic tumors may be underestimated.
牙源性肿瘤是起源于发育中牙胚各成分残余的病变。钙化囊性牙源性肿瘤或钙化牙源性囊肿是一种牙源性良性囊性肿瘤，其特征为成釉细胞瘤样上皮和影细胞。钙化囊性牙源性肿瘤可位于中央或周边，其影细胞可出现钙化，这一现象最早由戈林于1962年描述。大多数周边型钙化囊性牙源性肿瘤位于下颌骨或上颌骨的前牙龈。
作者报告一例上颌牙龈周边型钙化囊性牙源性肿瘤的罕见病例。一名39岁男性患者，左上尖牙附着颊侧牙龈出现一个纤维性肿物。肿物直径0.7厘米，无痛，临床诊断为周边型骨化性纤维瘤。切除活检后，诊断为周边型钙化囊性牙源性肿瘤。切除术后对患者进行了五年的监测，未发现复发。
所有活检材料都必须送去做组织学检查。如果不对外观无害的牙龈病变进行组织学检查，周边型钙化囊性牙源性肿瘤及其他周边型牙源性肿瘤的发生率可能会被低估。
