Radiology Department, Xiangyang NO.1 Hospital, The Affiliated Hospital of Hubei University of Medicine, Xiangyang, 441000, China.
Cardiovascular Medicine Department, Xiangyang NO.1 Hospital, The Affiliated Hospital of Hubei University of Medicine, Xiangyang, 441000, China.
J Formos Med Assoc. 2021 May;120(5):1171-1178. doi: 10.1016/j.jfma.2021.01.007. Epub 2021 Feb 12.
Gadolinium-enhanced magnetic resonance angiography (MRA) and computed tomography angiography (CTA) are commonly used for diagnosing renal arterial stenosis (RAS); however, the diagnostic value is yet controversial. The aim of the study was to evaluate the diagnostic values of both methods. Electronic databases, including PubMed, Embase, and the Cochrane Library, were searched for studies, since inception until October 2017. A total of four articles involving 486 subjects were included in the analysis. The summary of sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the receiver operating characteristic (ROC) (AUC) were 0.70, 0.82, 14.54, 0.29, 63.80, and 0.81 for MRA-based diagnosis of RAS, respectively. The pooled sensitivity, specificity, PLR, NLR, DOR, and AUC for CTA detecting RAS were 0.73, 0.96, 13.04, 0.29, 71.99, and 0.93, respectively. Gadolinium-enhanced MRA and CTA provide a satisfactory diagnostic accuracy, thereby playing a critical role in the diagnosis of RAS.
钆增强磁共振血管造影（MRA）和计算机断层血管造影（CTA）常用于诊断肾动脉狭窄（RAS）；然而，其诊断价值仍存在争议。本研究旨在评估这两种方法的诊断价值。电子数据库，包括 PubMed、Embase 和 Cochrane Library，自成立以来至 2017 年 10 月进行了研究检索。共有 4 篇文章涉及 486 名患者纳入分析。基于 MRA 诊断 RAS 的汇总敏感性、特异性、阳性似然比（PLR）、阴性似然比（NLR）、诊断比值比（DOR）和受试者工作特征曲线（ROC）下面积（AUC）分别为 0.70、0.82、14.54、0.29、63.80 和 0.81。CTA 检测 RAS 的汇总敏感性、特异性、PLR、NLR、DOR 和 AUC 分别为 0.73、0.96、13.04、0.29、71.99 和 0.93。钆增强 MRA 和 CTA 提供了令人满意的诊断准确性，因此在 RAS 的诊断中发挥着关键作用。
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