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围手术期心肌损伤与中高危心血管风险患者 2 型心肌梗死的发生率。

Perioperative myocardial damage and the incidence of type 2 myocardial infarction in patients with intermediate and high cardiovascular risk.

机构信息

Department of Internal Medicine, Medeniyet University Göztepe Education and Research Hospital, Istanbul Turkey.

Department of Oncology, Edirne Sultan 1. Murat State Hospital; Edirne-Turkey.

出版信息

Anatol J Cardiol. 2021 Feb;25(2):89-95. doi: 10.14744/AnatolJCardiol.2020.45752.

Abstract

OBJECTIVE

Perioperative myocardial infarction is a major cause of morbidity and mortality in patients undergoing surgical operations. We aimed to determine the incidence of perioperative myocardial infarction in patients with intermediate- or high-risk Framingham scores.

METHODS

One hundred and one patients (62 males, 39 females) over 40 years of age (mean age 72±11 years) median 73 (65-81), min- max (46-96), with Framingham risk scores of 10% or higher, and scheduled for surgical interventions in the orthopedics and urology departments of our hospital were included in the study. Patient demographics, comorbidities, blood pressures, and biochemical data were recorded. Troponin values and electrocardiographic findings were obtained during the immediate preoperative period and on postoperative day 2 and then compared. Perioperative myocardial injury and infarction were diagnosed using the third universal definition of myocardial infarction.

RESULTS

In 44 (43%) patients, postoperative troponin values were compared with the preoperative values. In 26 (25%) patients, the changes were consistent with myocardial ischemia or damage. Alterations in troponin values with significant electrocardiogram (ECG) changes were found in 6 patients (6%).

CONCLUSION

The risk of postoperative myocardial damage was high in our patients with intermediate or high-risk Framingham scores. This im-plies that close follow-up of these patients with abnormal ECG and troponin values during the pre- and postoperative period is required.

摘要

目的

围手术期心肌梗死是接受手术治疗的患者发病率和死亡率的主要原因。我们旨在确定具有中危或高危弗莱明翰评分的患者围手术期心肌梗死的发生率。

方法

101 例(62 例男性,39 例女性)年龄超过 40 岁(平均年龄 72±11 岁)中位数 73(65-81),最小值-最大值(46-96),弗莱明翰风险评分在 10%或更高,计划在我院骨科和泌尿科进行手术干预的患者纳入研究。记录患者的人口统计学、合并症、血压和生化数据。在术前和术后第 2 天获得肌钙蛋白值和心电图结果,然后进行比较。根据第三次心肌梗死通用定义诊断围手术期心肌损伤和梗死。

结果

在 44 例(43%)患者中,比较了术后肌钙蛋白值与术前值。在 26 例(25%)患者中,变化与心肌缺血或损伤一致。在 6 例患者(6%)中发现肌钙蛋白值改变伴明显心电图(ECG)改变。

结论

我们具有中危或高危弗莱明翰评分的患者术后心肌损伤的风险较高。这意味着需要密切监测这些患者在术前和术后期间心电图和肌钙蛋白值异常。

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