The Second Department of Internal Medicine, University of Occupational and Environmental Health, Japan.
Intern Med. 2021 Jul 15;60(14):2241-2244. doi: 10.2169/internalmedicine.6119-20. Epub 2021 Feb 15.
A 46-year-old man complained of chest pain at rest for the past three months. His symptoms gradually exacerbated and were suspected of being due to unstable angina. A coronary angiogram revealed focal tight stenosis at the proximal left anterior descending coronary artery with gross spastic coronary findings. Optical coherence tomography (OCT) revealed layered low-intensity structures with microvessels and the accumulation of macrophages, which indicated progressive stenosis with multiple-layered organized thrombus caused by coronary erosion. We treated the stenosis using a drug-coated balloon instead of drug-eluting stents. There was no restenosis, and OCT revealed good plaque healing at follow-up. This case suggests that the pre-interventional OCT plaque morphology can have a positive impact on the revascularization strategy.
一位 46 岁男性因过去三个月静息时胸痛而就诊。他的症状逐渐加重,疑似不稳定型心绞痛。冠状动脉造影显示左前降支近段局灶性严重狭窄,伴有明显的痉挛性冠状动脉改变。光学相干断层扫描(OCT)显示,伴有微血管和巨噬细胞聚集的分层低强度结构,提示由于冠状动脉侵蚀导致进行性狭窄和多层有组织的血栓形成。我们使用药物涂层球囊而非药物洗脱支架治疗狭窄。没有再狭窄,OCT 显示随访时斑块愈合良好。该病例提示,介入前 OCT 斑块形态可对血运重建策略产生积极影响。