Kumar Sumir, Kaur Amandeep, Kaur Sukhmani
Drs. Kumar and A. Kaur are with the Department of Dermatology, Leprology and Venereology at Guru Gobind Singh Medical College in Faridkot, Punjab, India.
Dr. S. Kaur is with Fortis Clinic, in Chandigarh, India.
J Clin Aesthet Dermatol. 2021 Jan;14(1):34-37. Epub 2021 Jan 1.
Dermatophytosis is one of the most common diseases worldwide and is difficult to treat due to its recalcitrant nature. Conventional treatment modalities are associated with frequent relapses due to the absence of a host immune interaction. Here, we present a case series of three patients with difficult-to-treat and recalcitrant dermatophytosis who were treated with homologous autoimplantation. Complete clearance of dermatophytosis was observed after three months in two of the patients and after two and a half months in one patient without the use of any antifungals. No relapses were observed within six months of follow-up. The outcomes of the three patients presented in this case series support homologous autoimplantation as a safe and effective procedure for the treatment of recalcitrant dermatophytosis. The procedure requires only a single visit that can be performed either alone or in combination with other modalities.
皮肤癣菌病是全球最常见的疾病之一,因其顽固性而难以治疗。由于缺乏宿主免疫相互作用,传统治疗方式常伴有频繁复发。在此,我们展示了一组三例难治性和顽固性皮肤癣菌病患者接受同种自体植入治疗的病例系列。两名患者在三个月后皮肤癣菌病完全清除,一名患者在两个半月后完全清除,且均未使用任何抗真菌药物。随访六个月内未观察到复发。该病例系列中三名患者的治疗结果支持同种自体植入作为治疗顽固性皮肤癣菌病的一种安全有效的方法。该方法仅需一次就诊,可单独进行或与其他方式联合进行。