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时空建模在低、中收入国家背景下行政二级儿童死亡率的研究

Space-time modeling of child mortality at the Admin-2 level in a low and middle income countries context.

机构信息

Department of Statistics, University of Washington, Washington, DC, USA.

Department of Biostatistics, University of Washington, Washington, DC, USA.

出版信息

Stat Med. 2021 Mar 30;40(7):1593-1638. doi: 10.1002/sim.8854. Epub 2021 Feb 14.

Abstract

The Sustainable Development Goals call for a total reduction of preventable child mortality before 2030. Further, the goals state the desirability to have subnational mortality estimates. Estimates at this level are required for health interventions at the subnational level. In a low and middle income countries context, the data on mortality typically consist of household surveys, which are carried out with a stratified, cluster design, and census microsamples. Most household surveys collect full birth history (FBH) data on birth and death dates of a mother's children, but censuses collect summary birth history (SBH) data which consist only of the number of children born and the number that died. In previous work, direct (survey-weighted) estimates with associated variances were derived from FBH data and smoothed in space and time. Unfortunately, the FBH data from household surveys are usually not sufficiently abundant to obtain yearly estimates at the Admin-2 level (at which interventions are often made). In this paper we describe four extensions to previous work: (i) combining SBH data with FBH data, (ii) modeling on a yearly scale, to combine data on a yearly scale with data at coarser time scales, (iii) adjusting direct estimates in Admin-2 areas where we do not observe any deaths due to small sample sizes, (iv) acknowledge differences in data sources by modeling potential bias arising from the various data sources. The methods are illustrated using household survey and census data from Kenya and Malawi, to produce mortality estimates from 1980 to the time of the most recent survey, and predictions to 2020.

摘要

可持续发展目标呼吁在 2030 年前将可预防的儿童死亡率全面降低。此外,目标还指出需要进行国家级以下的死亡率估计。在中低收入国家的背景下,死亡率数据通常包括家庭调查,这些调查采用分层、聚类设计和人口普查微样本进行。大多数家庭调查都收集了母亲子女的完整生育史(FBH)数据,包括出生日期和死亡日期,但人口普查只收集了简要生育史(SBH)数据,只包括出生的孩子数量和死亡的孩子数量。在之前的工作中,从 FBH 数据中推导出了直接(调查加权)估计值及其相关方差,并在空间和时间上进行了平滑处理。不幸的是,家庭调查中的 FBH 数据通常不够丰富,无法在行政 2 级(干预通常发生在该级别)获得每年的估计值。在本文中,我们描述了对以前工作的四项扩展:(i)将 SBH 数据与 FBH 数据相结合,(ii)进行年度建模,以将年度数据与更粗时间尺度的数据相结合,(iii)调整在我们没有观察到任何因样本量小而导致的死亡的行政 2 级地区的直接估计值,(iv)通过对来自各种数据源的潜在偏差进行建模来认识到数据来源的差异。这些方法使用来自肯尼亚和马拉维的家庭调查和人口普查数据进行了说明,以生成 1980 年至最近一次调查时间的死亡率估计值,并预测到 2020 年。

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