Department of Pharmacy, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan 528300, China.
Ji Hua Laboratory, Foshan 528200, China.
Chem Commun (Camb). 2021 Mar 11;57(21):2629-2632. doi: 10.1039/d0cc08089f.
In this work, we have developed a simple and reliable platform for simultaneous analysis of telomerase and miRNA. A three-dimensional bipedal DNA walking strategy is designed utilizing gold nanoparticles and MnO2 nanosheets. Given the merits of fast, sensitive and selective analysis, the developed method has great potential application in early clinical diagnosis.
在这项工作中，我们开发了一种简单可靠的端粒酶和 miRNA 同时分析平台。利用金纳米粒子和 MnO2 纳米片设计了一种三维双足 DNA 行走策略。鉴于其快速、灵敏和选择性分析的优点，该方法具有很大的临床早期诊断应用潜力。
