家族性阵发性共济失调的磁共振成像

Magnetic resonance imaging in familial paroxysmal ataxia.

作者信息

Vighetto A, Froment J C, Trillet M, Aimard G

机构信息

Service of Neurology, Hôpital Neurologique et Neurochirurgical Pierre Wertheimer, Lyon France.

出版信息

Arch Neurol. 1988 May;45(5):547-9. doi: 10.1001/archneur.1988.00520290083018.

DOI:10.1001/archneur.1988.00520290083018

PMID:3358708

Abstract

A magnetic resonance imaging study was performed in three symptomatic members of two families with a diagnosis of acetazolamide-responsive familial paroxysmal ataxia. A selective atrophy of the cerebellar vermis, mostly of the anterior part, was demonstrated in the three cases. The first ample documentation of a neuroanatomical abnormality in this condition was achieved in this study.

摘要

对两个被诊断为乙酰唑胺反应性家族性发作性共济失调的家族中的三名有症状成员进行了磁共振成像研究。在这三例病例中均显示出小脑蚓部存在选择性萎缩，主要是前部萎缩。本研究首次充分记录了这种疾病中的神经解剖学异常。