Department of Chemistry, Graduate School of Science, Osaka Prefecture University, Osaka, 599-8531, Japan.
Orig Life Evol Biosph. 2021 Mar;51(1):61-70. doi: 10.1007/s11084-021-09605-4. Epub 2021 Feb 15.
Gas-phase molecular adsorption was investigated as a model for molecular cloud formation. Molecular adsorption on cold gas-phase hydrogen-bonded clusters containing protonated tryptophan (Trp) enantiomers and monosaccharides such as methyl-α-D-glucoside, D-ribose, and D-arabinose was detected using a tandem mass spectrometer equipped with an electrospray ionization source and cold ion trap. The adsorption sites on the surface of cold gas-phase hydrogen-bonded cluster ions were quantified using gas-phase N adsorption-mass spectrometry. The gas-phase N adsorption experiments indicated that the number of adsorption sites on the surface of the hydrogen-bonded heterochiral clusters containing L-Trp and D-monosaccharides exceeded the number of adsorption sites on the homochiral clusters containing D-Trp and D-monosaccharides. HO molecules were preferentially adsorbed on the heterochiral clusters, and larger water clusters were formed in the gas phase. Physical and chemical properties of cold gas-phase hydrogen-bonded clusters containing biological molecules were useful for investigating enantiomer selectivity and chemical evolution in interstellar molecular clouds.
气相分子吸附被研究作为分子云形成的模型。使用配备电喷雾电离源和冷离子阱的串联质谱仪，检测到包含质子化色氨酸（Trp）对映异构体和单糖（如甲基-α-D-葡萄糖苷、D-核糖和 D-阿拉伯糖）的冷气相氢键簇上的分子吸附。使用气相 N 吸附-质谱法定量冷气相氢键簇离子表面上的吸附位。气相 N 吸附实验表明，包含 L-Trp 和 D-单糖的异手性氢键簇表面上的吸附位数量超过了包含 D-Trp 和 D-单糖的同手性氢键簇表面上的吸附位数量。HO 分子优先吸附在异手性簇上，并且在气相中形成更大的水簇。包含生物分子的冷气相氢键簇的物理和化学性质可用于研究星际分子云中的对映体选择性和化学演化。
