Rajiv Gandhi Centre for Diabetes and Endocrinology, Aligarh Muslim University, Aligarh, UP, India.
Department of Physiology, Aligarh Muslim University, Aligarh, UP, India.
Diabetes Metab Syndr. 2021 Jan-Feb;15(1):425-431. doi: 10.1016/j.dsx.2021.02.003. Epub 2021 Feb 5.
Though, the prevalence of diabetes is increasing in the worldwide, achievement of glycemic and non-glycemic targets remain suboptimal. We conducted this retrospective cross-sectional study at two endocrine clinics of Aligarh (Uttar Pradesh) in north India.
After screening the records of 13800 patients, 12140 patients of type 2 diabetes mellitus who were attending the clinic regularly every three to four months, were included in the final analysis. The data regarding patient's height, weight, body mass index, blood pressure, blood glucose, HbA1c, lipid profile and complications were obtained.
Mean age was 49.7 ± 11.3 years; males and females were almost equal in number. 2891 (23.8%) subjects were of age less than 40 years. 9614 (80%) patients had diabetes duration of less than 5 years. 3311 (27.3%) subjects were having an HbA1c of <7%, HbA1c 7-8% in 3711 (30.5%), HbA1c 8-9% in 2653 (21.9%) whereas HbA1c of >9% in 2465 (20.3%) subjects. The microvascular complications; diabetic nephropathy, diabetic neuropathy and diabetic retinopathy were present in 7.5%, 14.9% and 16.2% respectively. Hypertension was present in 25.8% and coronary artery disease was present in 15.5% of patients. Overall 27.3%, 41.7%, 44.1%, 45.3% and 67.7% of patients achieved their HbA1c, triglyceride, HDL, LDL and hypertension targets respectively, as per American Diabetes Association 2020 guidelines.
Despite availability of multiple drugs and guidelines, the attainment rates of glycemic and non-glycemic targets remain suboptimal. A more aggressive approach in the treatment of type 2 diabetes is required.
尽管全球范围内糖尿病的患病率正在上升，但血糖和非血糖目标的达标率仍不理想。我们在印度北部北方邦的两个内分泌诊所进行了这项回顾性横断面研究。
在筛选了 13800 名患者的记录后，将 12140 名经常每三到四个月定期到诊所就诊的 2 型糖尿病患者纳入最终分析。获得了患者身高、体重、体重指数、血压、血糖、HbA1c、血脂谱和并发症的数据。
平均年龄为 49.7 ± 11.3 岁；男女数量几乎相等。2891 名（23.8%）患者年龄小于 40 岁。9614 名（80%）患者的糖尿病病程小于 5 年。3311 名（27.3%）患者的 HbA1c<7%，HbA1c 为 7-8%的有 3711 名（30.5%），HbA1c 为 8-9%的有 2653 名（21.9%），而 HbA1c>9%的有 2465 名（20.3%）。微血管并发症；糖尿病肾病、糖尿病神经病变和糖尿病视网膜病变的发生率分别为 7.5%、14.9%和 16.2%。高血压的发生率为 25.8%，冠心病的发生率为 15.5%。根据美国糖尿病协会 2020 年的指南，总体上有 27.3%、41.7%、44.1%、45.3%和 67.7%的患者分别达到了他们的 HbA1c、甘油三酯、HDL、LDL 和高血压目标。
尽管有多种药物和指南可用，但血糖和非血糖目标的达标率仍不理想。需要更积极地治疗 2 型糖尿病。
