University Hospital for Urology, Klinikum Oldenburg, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, Oldenburg, Germany,
University Hospital for Urology, Klinikum Oldenburg, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.
Urol Int. 2021;105(7-8):574-580. doi: 10.1159/000513188. Epub 2021 Feb 15.
The objective of this study was to predict computed tomography (CT)-controlled treatment success after minimally invasive percutaneous nephrolithotomy (Mini-PCNL).
We relied on retrospective single institutional data from 92 kidney stone patients treated with Mini-PCNL. Residual stones after treatment were evaluated by post-Mini-PCNL CT scans. Stone-free status was defined as clinically insignificant residual stones ≤3 mm after surgery. Multivariable logistic regression analyses predicted stone-free status after Mini-PCNL.
Overall, 53 (57.6%) patients achieved stone-free status after Mini-PCNL treatment. In multivariable logistic regression analyses, stone localization was the strongest predictor for stone-free status after Mini-PCNL. Specifically, patients with exclusively pelvic stones were 7.1-fold more likely to achieve stone-free status than those patients with stones at multiple localizations (OR: 7.1; p = 0.005). Additionally, stone size represented a barrier for stone-free status (OR: 0.9; p = 0.03).
Stone localization revealed the highest impact on treatment success after Mini-PCNL. Especially, those patients with exclusively pelvic stones were most likely to achieve stone-free status. Conversely, patients with multiple stone localizations were less likely to achieve stone-free status and need to be informed about higher risk of additional interventions after initial Mini-PCNL.
本研究旨在预测微创经皮肾镜取石术(Mini-PCNL)后 CT 控制治疗的成功率。
我们依赖于 92 例接受 Mini-PCNL 治疗的肾结石患者的回顾性单机构数据。治疗后的残余结石通过术后 Mini-PCNL CT 扫描进行评估。结石清除状态定义为术后临床无意义的残余结石≤3mm。多变量逻辑回归分析预测 Mini-PCNL 后的结石清除状态。
总体而言,53 例(57.6%)患者在 Mini-PCNL 治疗后达到结石清除状态。在多变量逻辑回归分析中,结石定位是 Mini-PCNL 后结石清除状态的最强预测因素。具体来说,仅存在骨盆结石的患者比存在多个部位结石的患者更有可能达到结石清除状态(OR:7.1;p=0.005)。此外,结石大小也是结石清除状态的一个障碍(OR:0.9;p=0.03)。
结石定位对 Mini-PCNL 后治疗成功率的影响最大。特别是,那些仅存在骨盆结石的患者最有可能达到结石清除状态。相反,存在多个结石部位的患者达到结石清除状态的可能性较小,需要告知他们在初次 Mini-PCNL 后发生额外干预的风险更高。