Department of Anesthesiology, Cardiothoracic and Vascular Anesthesia, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Hamostaseologie. 2021 Feb;41(1):59-62. doi: 10.1055/a-1336-6116. Epub 2021 Feb 15.
Heparin-induced thrombocytopenia (HIT) is a severe, immune-mediated, adverse drug reaction that paradoxically induces a prothrombotic state. Particularly in the setting of cardiac surgery, where full anticoagulation is required during cardiopulmonary bypass, the management of HIT can be highly challenging, and requires a multidisciplinary approach. In this short review, the different perioperative strategies to run cardiopulmonary bypass will be summarized.
肝素诱导的血小板减少症（HIT）是一种严重的、免疫介导的药物不良反应，它会导致一种反常的血栓前状态。在心外科手术中，体外循环期间需要充分抗凝，HIT 的管理极具挑战性，需要多学科的方法。在这篇简短的综述中，我们将总结体外循环的不同围手术期策略。
