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三种不同国际标准在评估巴西儿童代谢综合征患病率中的应用。

Prevalence of metabolic syndrome in Brazilian children using three different sets of international criteria.

机构信息

Universidade Federal de Minas Gerais.

Universidade de Itaúna.

出版信息

Nutr Hosp. 2021 Apr 19;38(2):228-235. doi: 10.20960/nh.03224.

Abstract

Background: the aim of the present study was to compare the prevalence of metabolic syndrome in Brazilian children aged 6-10 years using three different international criteria. Methods: systolic and diastolic blood pressure (SBP and DBP), high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, triglycerides, fasting glucose, and insulin levels were measured in 290 schoolchildren, and the presence of metabolic syndrome was analyzed according to the criteria established by Cook, Boney, and Ferreira. Results: the prevalence of metabolic syndrome was 2.27 % (Boney and Ferreira criteria) and 7.58 % (Cook criteria) for girls, and 3.8 % (Boney and Ferreira criteria) and 5.06 % (Cook criteria) for boys. Agreement in pairs showed a concordance of 57.5 % (Kappa = 0.57) between Boney and Cook criteria, and 65.2 % (Kappa = 0.65) between Cook and Ferreira. The greatest concordance found was 77 % (Kappa = 0.77) between Boney and Ferreira criteria, demonstrating a substantial agreement. Conclusion: prevalence according to Boney and Ferreira criteria was lower than according to Cook criteria. Therefore, we suggest the use of Cook criteria in clinical practice for the diagnosis of metabolic syndrome, since this criterion provided a wider diagnostic range, thereby reducing the risk of underdiagnosis.

摘要

背景

本研究旨在比较三种不同的国际标准在评估巴西 6-10 岁儿童代谢综合征患病率方面的差异。方法:对 290 名在校儿童进行收缩压和舒张压(SBP 和 DBP)、高密度脂蛋白(HDL)胆固醇、低密度脂蛋白(LDL)胆固醇、甘油三酯、空腹血糖和胰岛素水平的检测,并根据 Cook、Boney 和 Ferreira 制定的标准分析代谢综合征的存在情况。结果:女孩中代谢综合征的患病率分别为 2.27%(Boney 和 Ferreira 标准)和 7.58%(Cook 标准),男孩中分别为 3.8%(Boney 和 Ferreira 标准)和 5.06%(Cook 标准)。两两比较显示,Boney 和 Cook 标准之间的一致性为 57.5%(Kappa = 0.57),Cook 和 Ferreira 标准之间的一致性为 65.2%(Kappa = 0.65)。Boney 和 Ferreira 标准之间的最大一致性为 77%(Kappa = 0.77),显示出高度一致性。结论:根据 Boney 和 Ferreira 标准的患病率低于根据 Cook 标准的患病率。因此,我们建议在临床实践中使用 Cook 标准来诊断代谢综合征,因为该标准提供了更广泛的诊断范围,从而降低了漏诊的风险。

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