Asnis G M, Leopold M A, Duvoisin R C, Schwartz A H
Am J Psychiatry. 1977 Dec;134(12):1367-70. doi: 10.1176/ajp.134.12.1367.
The authors found a high prevalence--43.4% of tardive dyskinesia in a sample of psychiatric outpatients, a population previously thought to be at nominal risk for development of this syndrome. There was no significant relationship between the presence of dyskinesia and age, sex, years of neuroleptic use, or various organic factors. The effects of dentures and of drug combinations are discussed, and it is noted that structured scales of dyskinesia and videotope recordings are important tools in diagnosing and following the course of dyskinesia.
作者们在一组精神科门诊患者样本中发现迟发性运动障碍的患病率很高——达43.4%,而该人群此前被认为患此综合征的风险很低。运动障碍的出现与年龄、性别、使用抗精神病药物的年限或各种器质性因素之间没有显著关系。文中讨论了假牙和药物组合的影响,并指出运动障碍结构化量表和录像记录是诊断和跟踪运动障碍病程的重要工具。