盐酸纳洛酮治疗精神分裂症的知觉障碍。

The treatment of perceptual disturbances in schizophrenia with naloxone hydrochloride.

作者信息

Kurland A A, McCabe O L, Hanlon T E, Sullivan D

出版信息

Am J Psychiatry. 1977 Dec;134(12):1408-10. doi: 10.1176/ajp.134.12.1408.

DOI:10.1176/ajp.134.12.1408

Abstract

The authors treated 12 schizophrenic patients who had overt hallucinatory symptoms with intravenously administered naloxone hydrochloride, a narcotic antagonist purported to have antihallucinatory properties. They found no evidence of the effectiveness of naloxone in preventing hallucinations over that of placebo when administered in a randomized, double-blind fashion.

摘要

作者对12名有明显幻觉症状的精神分裂症患者静脉注射盐酸纳洛酮（一种据称具有抗幻觉特性的麻醉拮抗剂）进行治疗。他们发现，在随机双盲给药时，没有证据表明纳洛酮在预防幻觉方面比安慰剂更有效。