Sarkisov D S, Kolokol'chikova E G, Kaem R I, Pal'tsyn A A
Biull Eksp Biol Med. 1988 Apr;105(4):501-3.
Granulation tissue was examined in rats on the 20th and 40th day after wounding of the back. It was shown that by both the 20th and the 40th day the vessels with impaired typical structure could be revealed together with the normal ones in the granulation tissue. Specific rearrangement was observed in the structure of these vessels, consisting in the impairment of their wall integrity, separation of the constituent cells and their free position among the other cells and fibrous structures. This process is especially marked by the 40th day. 3H-thymidine was actively incorporated by some fibroblasts and rather often by the cells of both normal and degenerating vessels. The authors suggest the existence of an earlier unknown phenomenon of transformation of capillary vessels, common for both normal dermal and reparative processes after injury. The essence of the phenomenon consists in the fact that small dermal vessels get permanently disintegrated and are included into the composition of cellular elements of the interstitial tissue, and form again, providing for the physiological regeneration of dermal cells and fibrous structures.
在大鼠背部受伤后的第20天和第40天对肉芽组织进行了检查。结果表明，在第20天和第40天，肉芽组织中均可发现典型结构受损的血管以及正常血管。在这些血管的结构中观察到了特异性重排，表现为血管壁完整性受损、组成细胞分离以及它们在其他细胞和纤维结构中的游离状态。到第40天时，这一过程尤为明显。一些成纤维细胞以及正常和退化血管的细胞都活跃地掺入了3H-胸腺嘧啶核苷。作者认为存在一种此前未知的毛细血管转化现象，这在正常皮肤和损伤后的修复过程中都很常见。该现象的本质在于，小的皮肤血管会永久性解体并融入间质组织的细胞成分中，然后再次形成，为皮肤细胞和纤维结构的生理再生提供条件。
