Department of Psychology, University of Hildesheim, Hildesheim, Germany.
Department of Clinical Psychology and Psychotherapy, University of Hildesheim, Universitätsplatz 1, 31141, Hildesheim, Germany.
Qual Life Res. 2021 Jul;30(7):1985-1995. doi: 10.1007/s11136-021-02772-x. Epub 2021 Feb 15.
According to estimations of the World Health Organization, depressive disorders, and cardiovascular disease will be the leading causes for global burden of disease in 2030. The aim of the present study was to estimate the value a representative sample of the German population places on quality-adjusted life years (QALYs) for depressive disorders compared to heart disease.
A representative sample of N = 967 of the German general public was randomly presented with one of two hypothetical health-loss scenarios: One version of the questionnaire presented respondents with health loss due to depression, while the other version dealt with health loss due to experiencing a heart disease. Respondents were asked to indicate their willingness to pay (WTP) for four hypothetical health-gain scenarios with different treatment options.
In the depression questionnaire median WTP values ranged from 1000 to 1500 EUR; in the heart disease questionnaire from 1000 to 2000 EUR. Results of the Mann-Whitney U-Test and Median Test indicate higher WTP values for heart disease compared to depressive disorders when QALY gains were minor and stretched over a long period of time, and when treatment with bypass operation (rather than treatment with ECT) was offered. Zero WTP was significantly higher in all scenarios of the depression questionnaire in comparison to the hearth disease questionnaire.
Results indicate that respondents valued the necessity of paying for treatment higher when presented with heart disease compared to depression.
根据世界卫生组织的估计，到 2030 年，抑郁障碍和心血管疾病将成为全球疾病负担的主要原因。本研究旨在评估德国有代表性的人群样本对抑郁障碍（与心脏病相比）调整后的生命质量（QALY）的重视程度。
采用随机抽样的方法，对德国普通公众中的 967 名代表样本进行了问卷调查，其中一个版本的问卷呈现了因抑郁而导致的健康损失，而另一个版本则涉及因心脏病而导致的健康损失。受访者被要求对四个不同治疗方案的假设健康获益场景表明其支付意愿（WTP）。
在抑郁问卷中，中位数 WTP 值范围在 1000 至 1500 欧元之间；在心脏病问卷中，中位数 WTP 值范围在 1000 至 2000 欧元之间。Mann-Whitney U 检验和中位数检验的结果表明，当 QALY 增益较小且持续时间较长，以及提供旁路手术（而不是 ECT 治疗）时，与抑郁障碍相比，受访者对心脏病的 WTP 值更高。在所有抑郁问卷的情景中，零 WTP 显著高于心脏病问卷。
结果表明，与抑郁障碍相比，当呈现心脏病时，受访者对治疗的必要性支付意愿更高。
