Department of Diagnosis and Therapeutics, School of Dentistry (UERJ), State University of Rio de Janeiro, Rio de Janeiro, Brazil.
Oral Medicine, São Leopoldo Mandic School, Rio de Janeiro, Brazil.
Gerodontology. 2021 Sep;38(3):317-320. doi: 10.1111/ger.12521. Epub 2021 Feb 16.
Nasolabial Cyst (NC) or Klestadt's cyst is a relatively rare soft tissue developmental lesion of nasal alar region accounting for 0.7% of all non-odontogenic cysts. NC usually presents as an asymptomatic swelling located in the anterior region of the maxilla lateral to midline-resulting in obliteration of nasolabial sulcus, nasal vestibule and maxillary labial sulcus and facial asymmetry-often observed on early stages by most patients due to cosmetics issues.
A 76-year-old woman was referred for evaluation of an asymptomatic facial swelling in the left upper lip region lasting 20 years. Extraoral clinical examination showed a left-sided swelling lateral to midline near to the alar base resulting in facial asymmetry. Intraoral clinical examination revealed the presence of a single painless well-defined nodular, sessile, non-tender swelling covered by normal oral mucosa, and located in the upper labial mucosa in the left incisor's region. An excisional biopsy was performed, and microscopic examination revealed a cystic cavity lined by cuboidal to columnar epithelium with mucous cells. The underlying connective tissue showed chronic inflammatory infiltrate close to muscular tissue. Patient recovery was uneventful, and there are no signs of local recurrence in a 2-year clinical follow-up.
Clinicians should consider NC when evaluating an upper lip swelling extending to the nasolabial region of the elders.
鼻唇囊肿(NC)或 Klestadt 囊肿是一种罕见的鼻侧区软组织发育性病变,占所有非牙源性囊肿的 0.7%。NC 通常表现为无症状的肿胀,位于上颌骨中线外侧的前区域,导致鼻唇沟、鼻前庭和上颌唇沟消失,并导致面部不对称——由于美容问题,大多数患者在早期就能观察到这种情况。
一名 76 岁女性因左侧上唇区域无症状肿胀 20 年就诊。口腔外临床检查显示中线旁左侧靠近鼻翼基底的肿胀,导致面部不对称。口腔内临床检查显示存在单个无痛性界限清楚的结节状、无蒂、无触痛肿胀,被正常口腔黏膜覆盖,位于左上唇黏膜的左侧切牙区域。进行了切除活检,显微镜检查显示囊性腔由立方到柱状上皮和黏液细胞衬里。下方的结缔组织靠近肌肉组织有慢性炎症浸润。患者恢复顺利,在 2 年的临床随访中无局部复发迹象。
当评估延伸至鼻唇区域的老年人上唇肿胀时,临床医生应考虑 NC。