大鼠额叶皮质中胆碱乙酰转移酶免疫阳性锥体细胞

Choline acetyltransferase immunopositive pyramidal neurons in the rat frontal cortex.

作者信息

Nishimura Y, Natori M, Mato M

机构信息

Department of Anatomy, Jichi Medical School, Tochigi-Ken, Japan.

出版信息

Brain Res. 1988 Feb 2;440(1):144-8. doi: 10.1016/0006-8993(88)91166-3.

DOI:10.1016/0006-8993(88)91166-3

PMID:3359203

Abstract

The putative cholinergic neurons of the rat's frontal cortex (Krieg's area 10) were studied using monoclonal antibody to choline acetyltransferase (ChAT). This paper reports two novel findings which might be very important to reason the function of the frontal cortex. Firstly, the immunopositive cells were distributed in layers II, IV, V and VI around the rostral half, and layers IV, V and VI around the caudal half of Krieg's area 10. Secondly, the majority of immunopositive neurons in layer V was pyramidal cell.

摘要

使用抗胆碱乙酰转移酶（ChAT）单克隆抗体对大鼠额叶皮质（克里格10区）的假定胆碱能神经元进行了研究。本文报告了两项新发现，这可能对推断额叶皮质的功能非常重要。首先，免疫阳性细胞分布在克里格10区 Rostral 半部周围的II、IV、V和VI层，以及尾侧半部周围的IV、V和VI层。其次，V层中的大多数免疫阳性神经元是锥体细胞。