Choline acetyltransferase immunopositive pyramidal neurons in the rat frontal cortex.

The putative cholinergic neurons of the rat's frontal cortex (Krieg's area 10) were studied using monoclonal antibody to choline acetyltransferase (ChAT). This paper reports two novel findings which might be very important to reason the function of the frontal cortex. Firstly, the immunopositive cells were distributed in layers II, IV, V and VI around the rostral half, and layers IV, V and VI around the caudal half of Krieg's area 10. Secondly, the majority of immunopositive neurons in layer V was pyramidal cell.