松果体-视网膜分子关系；松果体换能器中27 kDa钙结合蛋白的免疫细胞化学证据

Pineal-retinal molecular relationships; immunocytochemical evidence of calbindin-27 kDa in pineal transducers.

作者信息

Roman A, Brisson P, Pasteels B, Demol S, Pochet R, Collin J P

机构信息

Laboratory of Histology, Faculty of Medicine, Université Libre de Bruxelles, Belgium.

出版信息

Brain Res. 1988 Feb 23;442(1):33-42. doi: 10.1016/0006-8993(88)91429-1.

DOI:10.1016/0006-8993(88)91429-1

PMID:3359254

Abstract

Calbindin-27 kDa immunocytochemical localization was studied concurrently in the pineal organ and retina from human as well as representatives of all vertebrate classes. Calbindin immunoreactivity was demonstrated in retinal cones (but not in rods) and in pineal transducers (cone-like and modified photoreceptor cells, pinealocytes) of a majority of amniotes. In contrast, no labelling was observed in anamniotes, except in retinal cones of the toad. Labelling was distributed through all cellular compartments (outer and inner segments, perikarya, pedicles or processes) of pineal transducers and retinal cones. Intra- and interspecific variations of calbindin contents are discussed.

摘要

对人类以及所有脊椎动物类群代表的松果体器官和视网膜中27 kDa钙结合蛋白进行了免疫细胞化学定位研究。在大多数羊膜动物的视网膜视锥细胞（而非视杆细胞）和松果体换能器（类视锥和经过修饰的光感受器细胞、松果体细胞）中发现了钙结合蛋白免疫反应性。相比之下，除蟾蜍的视网膜视锥细胞外，无羊膜动物未观察到标记。标记分布于松果体换能器和视网膜视锥细胞的所有细胞区室（外段和内段、核周体、蒂或突起）。文中讨论了钙结合蛋白含量的种内和种间差异。