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起源于颅神经的颅外硬脑膜海绵状血管畸形:病例报告及文献复习。

Calcified extra-axial cavernous malformation arising from lower cranial nerves: A case report and literature review.

机构信息

Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, Sichuan.

Department of Neurosurgery, Nanchong Central Hospital, The Second Clinical Medical College of North Sichuan Medical College, Nanchong, China.

出版信息

Medicine (Baltimore). 2021 Feb 5;100(5):e24566. doi: 10.1097/MD.0000000000024566.

Abstract

RATIONALE

Extra-axial cavernous malformations (ECMs) arising from cranial nerves (CNs) are rare. Complete "en bloc" lesion resection and hemosiderin-stained tissue preservation remain the standard treatment, while a different strategy may be needed when the lesion is highly calcified . We report the 3rd calcified ECM-CN and review the clinical features and surgical strategy for this rare condition considering previous literature.

PATIENT CONCERNS

We present a 52-year-old woman with a calcified lesion located in the right lower 1/3 of the cerebellopontine angle.

DIAGNOSIS

The diagnosis was calcified ECM-CNs according to the pathological and radiological features.

INTERVENTIONS

A posterior midline craniotomy was performed, and piecemeal resection of the lesion was carried out. Subtotal resection of the lesion was achieved with a small piece left in situ.

OUTCOMES

No symptom or lesion-related recurrence was found during 28 months of follow-up.

LESSONS

Calcified ECM-CNs are unique cavernous malformations arising from CNs. Piecemeal resection and subtotal or near-total excision are 2 major aspects that differ from the surgical strategy for general ECM-CNs.

摘要

背景

起源于颅神经(CNs)的颅外海绵状畸形(ECMs)很少见。完整的“整块”病变切除术和含铁血黄素染色组织保存仍然是标准治疗方法,而当病变高度钙化时,可能需要不同的策略。我们报告了第 3 例钙化 ECM-CN,并结合以往文献回顾了这种罕见疾病的临床特征和手术策略。

患者关注

我们报告了一例 52 岁女性,其钙化病变位于桥小脑角的右下 1/3 处。

诊断

根据病理和影像学特征,诊断为钙化 ECM-CNs。

干预措施

行后正中开颅术,分块切除病变。总切除量为部分切除,一小部分留在原位。

结果

28 个月的随访中未发现症状或与病变相关的复发。

经验教训

钙化 ECM-CNs 是起源于 CNs 的独特海绵状畸形。与一般 ECM-CNs 的手术策略不同,其主要方面有两点,即分块切除术和次全或近全切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6d7/7870219/eff5bca9e843/medi-100-e24566-g001.jpg

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