Translational Research Laboratory, Department of Research, Infectious Diseases Institute, College of Health Sciences, Makerere University, P.O Box 22418, Kampala, Uganda.
Department of Medicine, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
J Transl Med. 2021 Feb 16;19(1):76. doi: 10.1186/s12967-021-02747-z.
Translational research is a process of applying knowledge from basic biology and clinical trials to techniques and tools that address critical medical needs. Translational research is less explored in the Ugandan health system, yet, it is fundamental in enhancing human health and well-being. With the current high disease burden in Uganda, there are many opportunities for exploring, developing and utilising translational research.
In this article, we described the current state, barriers and opportunities for translational research in Uganda. We noted that translational research is underutilised and hindered by limited funding, collaborations, laboratory infrastructure, trained personnel, equipment and research diversity. However, with active collaborations and funding, it is possible to set up and develop thriving translational research in Uganda. Researchers need to leverage existing international collaborations to enhance translational research capacity development.
Expanding the integration of clinical and translational research in Uganda health care system will improve clinical care.
转化研究是将基础生物学和临床试验中的知识应用于解决关键医疗需求的技术和工具的过程。转化研究在乌干达卫生系统中探索较少，但它对增强人类健康和福祉至关重要。随着乌干达目前疾病负担高，有许多机会可以探索、开发和利用转化研究。
本文描述了乌干达转化研究的现状、障碍和机遇。我们注意到，转化研究的利用不足，受到资金有限、合作、实验室基础设施、训练有素的人员、设备和研究多样性的限制。然而，通过积极的合作和资金，有可能在乌干达建立和发展繁荣的转化研究。研究人员需要利用现有的国际合作来加强转化研究能力的发展。
扩大临床和转化研究在乌干达医疗保健系统中的整合将改善临床护理。
