使用O-(2,3,4-三-O-乙酰基-α-L-呋喃岩藻糖基)-(1→3)-O-(2-乙酰氨基-4,6-二-O-乙酰基-2-脱氧-β-D-吡喃葡萄糖基)-(1→3)-2,4,6-三-O-乙酰基-α-D-吡喃半乳糖基溴作为糖基供体。4-硝基苯基O-α-L-呋喃岩藻糖基-(1→3)-O-(2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基)-(1→3)-β-D-吡喃半乳糖苷的合成。 - Suppr

Use of O-(2,3,4-tri-O-acetyl-alpha-L-fucopyranosyl)-(1----3)-O-(2-acetamido- 4,6-di-O-acetyl-2-deoxy-beta-D-glucopyranosyl)-(1----3)-2,4,6-tri-O- acetyl-alpha-D-galactopyranosyl bromide as a glycosyl donor. Synthesis of 4-nitrophenyl O-alpha-L-fucopyranosyl-(1----3)-O-(2-acetamido-2-deoxy-beta-D- glucopyranosyl)-(1----3)-beta-D-galactopyranoside.

作者信息

Jain R K, Abbas S A, Matta K L

机构信息

Department of Gynecologic Oncology, Roswell Park Memorial Institute, New York State Department of Health, Buffalo 14263.

出版信息

Carbohydr Res. 1988 Mar 1;173(2):297-302. doi: 10.1016/s0008-6215(00)90826-7.

DOI:10.1016/s0008-6215(00)90826-7

PMID:3359457

Abstract

摘要

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Use of O-(2,3,4-tri-O-acetyl-alpha-L-fucopyranosyl)-(1----3)-O-(2-acetamido- 4,6-di-O-acetyl-2-deoxy-beta-D-glucopyranosyl)-(1----3)-2,4,6-tri-O- acetyl-alpha-D-galactopyranosyl bromide as a glycosyl donor. Synthesis of 4-nitrophenyl O-alpha-L-fucopyranosyl-(1----3)-O-(2-acetamido-2-deoxy-beta-D- glucopyranosyl)-(1----3)-beta-D-galactopyranoside.使用O-(2,3,4-三-O-乙酰基-α-L-呋喃岩藻糖基)-(1→3)-O-(2-乙酰氨基-4,6-二-O-乙酰基-2-脱氧-β-D-吡喃葡萄糖基)-(1→3)-2,4,6-三-O-乙酰基-α-D-吡喃半乳糖基溴作为糖基供体。4-硝基苯基O-α-L-呋喃岩藻糖基-(1→3)-O-(2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基)-(1→3)-β-D-吡喃半乳糖苷的合成。

Carbohydr Res. 1988 Mar 1;173(2):297-302. doi: 10.1016/s0008-6215(00)90826-7.

Synthetic mucin fragments. Methyl 6-O-(2-acetamido-2-deoxy-beta-D- glucopyranosyl)-beta-D-galactopyranoside, methyl 3,4-di-O-(2-acetamido-2-deoxy- beta-D-glucopyranosyl)-beta-D-galactopyranoside, and methyl O-(2-acetamido-2- deoxy-beta-D-glucopyranosyl)-(1----3)-O-beta-D-galactopyranosyl-(1---- 3)-O-(2- acetamido-2-deoxy-beta-D-glucopyranosyl)-(1----3)-beta-D-galactopyr ano side.合成粘蛋白片段。6-O-（2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基）-β-D-吡喃半乳糖苷甲酯、3,4-二-O-（2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基）-β-D-吡喃半乳糖苷甲酯和O-（2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基）-（1→3）-O-β-D-吡喃半乳糖基-（1→3）-O-（2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基）-（1→3）-β-D-吡喃半乳糖苷甲酯。

Carbohydr Res. 1987 Mar 15;161(1):39-47. doi: 10.1016/0008-6215(87)84004-1.

Synthesis of benzyl 2-acetamido-2-deoxy-3-O-beta-D-fucopyranosyl-alpha-D-galactopyranoside and benzyl 2-acetamido-6-O-(2-acetamido-2-deoxy-beta- D-glucopyranosyl)-2-deoxy-3-O-beta-D-fucopyranosyl-alpha-D- galactopyranoside.2-乙酰氨基-2-脱氧-3-O-β-D-岩藻糖基-α-D-吡喃半乳糖苷苄酯和2-乙酰氨基-6-O-(2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基)-2-脱氧-3-O-β-D-岩藻糖基-α-D-吡喃半乳糖苷苄酯的合成

Carbohydr Res. 1984 Aug 15;131(2):257-63. doi: 10.1016/0008-6215(84)85247-7.

Synthetic mucin fragments. Benzyl O-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-(1----3)-O-beta-D- galactopyranosyl-(1----3)-O-[(2-acetamido-2-deoxy-beta-D-glucopyran osy l)- (1----6)]-2-acetamido-2-deoxy-alpha-D-galactopyranoside and benzyl O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-(1----3)-O-beta-D- galactopyranosyl-(1----3)-O-[beta-D-galactopyranosyl-(1----6)]-2-ac eta mido- 2-deoxy-alpha-D-galactopyranoside.合成粘蛋白片段。苄基 O-(2-乙酰氨基-2-脱氧-α-D-吡喃葡萄糖基)-(1→3)-O-β-D-吡喃半乳糖基-(1→3)-O-[(2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基)-(1→6)]-2-乙酰氨基-2-脱氧-α-D-吡喃半乳糖苷和苄基 O-(2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基)-(1→3)-O-β-D-吡喃半乳糖基-(1→3)-O-[β-D-吡喃半乳糖基-(1→6)]-2-乙酰氨基-2-脱氧-α-D-吡喃半乳糖苷。

Carbohydr Res. 1988 Dec 1;183(2):163-73. doi: 10.1016/0008-6215(88)84071-0.

Further use of O-(2,3,4-tri-O-acetyl-alpha-L-fucopyranosyl)-(1----3)-O-(2-acetamido-4 ,6-di-O- acetyl-2-deoxy-beta-D-glucopyranosyl)-(1----3)-2,4,6-tri-O-acetyl-a lph a-D- galactopyranosyl bromide as a glycosyl donor. Synthesis of two mucin-type tetrasaccharides.

Carbohydr Res. 1988 Oct 1;181:236-41. doi: 10.1016/0008-6215(88)84041-2.

Synthetic mucin fragments: benzyl 2-acetamido-6-O-(2-acetamido-2-deoxy-beta- D-glucopyranosyl)-2-deoxy-3-O-beta-D-galactopyranosyl-alpha-D- galactopyranoside and benzyl 2-acetamido-6-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)- 3-O-[6-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-beta-D- galactopyranosyl]-2-deoxy-alpha-D-galactopyranoside.合成粘蛋白片段：苄基2-乙酰氨基-6-O-（2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基）-2-脱氧-3-O-β-D-吡喃半乳糖基-α-D-吡喃半乳糖苷和苄基2-乙酰氨基-6-O-（2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基）-3-O-[6-O-（2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基）-β-D-吡喃半乳糖基]-2-脱氧-α-D-吡喃半乳糖苷。

Carbohydr Res. 1984 Mar 1;126(1):115-24. doi: 10.1016/0008-6215(84)85130-7.

Synthesis of O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-(1----3)-O-beta-D- galactopyranosyl-(1----4)-2-acetamido-2-deoxy-D-glucopyranose and two related trisaccharides containing the "lacto-N-biose II" unit.O-（2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基）-（1→3）-O-β-D-吡喃半乳糖基-（1→4）-2-乙酰氨基-2-脱氧-D-吡喃葡萄糖及两种含有“乳糖-N-二糖II”单元的相关三糖的合成

Carbohydr Res. 1987 Nov 15;169:201-12. doi: 10.1016/0008-6215(87)80251-3.

Preparation, characterization, and biological evaluation of 6(I),6(IV)-di-O-[α-l-fucopyranosyl-(1→6)-2-acetamido-2-deoxy-β-d-glucopyranosyl]-cyclomaltoheptaose and 6-O-[α-l-fucopyranosyl-(1→6)-2-acetamido-2-deoxy-β-d-glucopyranosyl]-cyclomaltoheptaose.6(I),6(IV)-二-O-[α-L-岩藻吡喃糖基-(1→6)-2-乙酰氨基-2-去氧-β-D-吡喃葡萄糖基]-环麦芽七糖和 6-O-[α-L-岩藻吡喃糖基-(1→6)-2-乙酰氨基-2-去氧-β-D-吡喃葡萄糖基]-环麦芽七糖的制备、表征和生物学评价。

Carbohydr Res. 2011 Sep 27;346(13):1792-800. doi: 10.1016/j.carres.2011.06.013. Epub 2011 Jun 15.

Synthetic mucin fragments. Benzyl O-beta-D-galactopyranosyl-(1----3)-O-(2-acetamido-2-deoxy-beta-D- glucopyranosyl)-(1----6)-2-acetamido-2-deoxy-alpha-D-galactopyranoside and O-alpha-L-fucopyranosyl-(1----3)-O-(2-acetamido-2-deoxy-beta-D- glucopyranosyl)-(1----6)-2-acetamido-2-deoxy-D-galactopyranose.合成粘蛋白片段。苄基 O-β-D-吡喃半乳糖基-(1→3)-O-(2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基)-(1→6)-2-乙酰氨基-2-脱氧-α-D-吡喃半乳糖苷和 O-α-L-吡喃岩藻糖基-(1→3)-O-(2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖基)-(1→6)-2-乙酰氨基-2-脱氧-D-吡喃半乳糖

Carbohydr Res. 1989 Jun 15;189:21-30. doi: 10.1016/0008-6215(89)84083-2.

Synthesis of a fucosylated and a non-fucosylated core structure of xylose-containing carbohydrate chains from N-glycoproteins.从N-糖蛋白合成含木糖碳水化合物链的岩藻糖基化和非岩藻糖基化核心结构。

Carbohydr Res. 1994 Nov 1;264(1):45-62. doi: 10.1016/0008-6215(94)00187-1.

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