Department of Clinical Research, University of Southern Denmhark, Odense, Denmark.
Department of Obstetrics and Gynaecology, Kilimanjaro Christian Medical Center, Moshi, Tanzania.
Acta Obstet Gynecol Scand. 2021 Apr;100(4):619-628. doi: 10.1111/aogs.14127. Epub 2021 Mar 16.
Unintended pregnancy, a major global health issue resulting in unsafe terminations of pregnancy and maternal deaths in low- and middle-income countries, could be significantly reduced through increased use of modern contraception, including long-acting reversible contraceptives (LARC). Training of healthcare providers to administer such contraceptives may improve uptake. We conducted a systematic review to collate the end-user uptake data following training of healthcare providers in low- and middle-income countries.
We searched PubMed, Embase, the Global Health Library and the Cochrane Library up to 23 May 2020. The review was restricted to low- and middle-income countries and focused on healthcare providers who had received training in LARC. Studies that reported contraceptive uptake among women, preference of LARC among healthcare workers and/or women, and unplanned pregnancies within 12 months of LARC initiation were included. All included studies underwent quality assessment using either the Cochrane Risk of Bias Tool or the Newcastle-Ottawa Scale. PROSPERO registration number CRD42020185291.
A total of 28 studies (end-users n = 6 112 544) were included (27 cohort studies and one randomized trial). Nineteen studies were set in Africa, five in Asia, one in Central America and four were multi-country studies. Twenty-eight studies reported LARC use among women, and 25 studies found an increase in uptake of LARC by women using short-acting methods switching to longer-acting methods or by recruiting new users of LARC. The randomized controlled trial was assessed as high quality and reported positive findings; however, there was great heterogeneity in the type of intervention and of how outcomes were measured among the other included studies. Further, the quality of these studies varied, although it should be noted that the poor-quality studies reflected the trends of those of higher quality.
Despite heterogeneity, current evidence indicates that training of healthcare providers in LARC may increase the uptake among women in low- and middle-income countries. More robust studies are warranted to inform policy.
意外怀孕是一个全球性的重大健康问题,导致中低收入国家不安全的终止妊娠和孕产妇死亡,通过增加现代避孕措施的使用,包括长效可逆避孕措施(LARC),可以显著减少这种情况。培训医疗保健提供者来管理这些避孕措施可能会提高使用率。我们进行了一项系统评价,以整理在中低收入国家培训医疗保健提供者后最终用户使用数据。
我们在 2020 年 5 月 23 日之前检索了 PubMed、Embase、全球卫生图书馆和 Cochrane 图书馆。该评价仅限于中低收入国家,重点关注接受 LARC 培训的医疗保健提供者。包括报告妇女避孕措施使用率、卫生工作者和/或妇女对 LARC 的偏好以及 LARC 启动后 12 个月内计划外怀孕的研究。所有纳入的研究均使用 Cochrane 偏倚风险工具或 Newcastle-Ottawa 量表进行质量评估。PROSPERO 注册号 CRD42020185291。
共纳入 28 项研究(最终用户 n=6112544)(27 项队列研究和 1 项随机试验)。19 项研究在非洲进行,5 项在亚洲,1 项在中美洲,4 项是多国家研究。28 项研究报告了妇女使用 LARC,25 项研究发现使用短效方法的妇女改用长效方法或招募新的 LARC 用户,LARC 的使用率增加。随机对照试验被评估为高质量,报告了积极的结果;然而,纳入的其他研究中,干预措施的类型和结果的测量方式存在很大差异。此外,这些研究的质量参差不齐,尽管应该注意到,低质量的研究反映了高质量研究的趋势。
尽管存在异质性,但现有证据表明,培训医疗保健提供者使用 LARC 可能会提高中低收入国家妇女的使用率。需要进行更有力的研究,为政策提供信息。