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OPTN/SRTR 2019 年度数据报告:肠。

OPTN/SRTR 2019 Annual Data Report: Intestine.

机构信息

Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute, Minneapolis, MN.

Liver and Intestine Transplantation Program, Seattle Children's Hospital, Seattle, WA.

出版信息

Am J Transplant. 2021 Feb;21 Suppl 2:316-355. doi: 10.1111/ajt.16498.

Abstract

Intestine transplant can be life-saving and can improve quality of life for patients with intestinal failure. Medical and surgical advances in treatment of intestinal failure over the past 10 to 15 years have resulted in fewer patients being added to the waiting list for intestine transplant alone or for intestine transplant in combination with liver transplant (and sometimes other organs). Consequently, fewer transplants are being performed. The numbers of listings and transplants fell to new lows in 2019. The number of programs performing transplants in at least one patient in 2019 was the lowest in the last decade, equal to 2014, at 15. Graft failure plateaued over the past decade, but early graft loss has increased in the past 2 years, notably in recipients of a combined liver and intestine allograft. Five-year patient survival for transplants in 2012-2014 varied little by graft type.

摘要

肠移植可以救命,并能提高肠衰竭患者的生活质量。过去 10 到 15 年中,肠衰竭治疗方面的医学和外科进步使单独接受肠移植或同时接受肠移植和肝移植(有时还包括其他器官)的患者人数减少,因此移植手术数量也随之减少。2019 年,移植的例数和数量降至新低。2019 年,至少对一名患者进行移植的项目数量为十年来最低,与 2014 年持平,为 15 个。过去十年,移植物失功保持稳定,但过去两年早期移植物损失有所增加,尤其是接受肝肠联合移植的患者。2012-2014 年,不同移植物类型的患者术后 5 年生存率差异不大。

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