Tognoli S, Astuni M, Zampriolo P, Pasolini E, Bianchi P, Fantoni P A
Ospedale di Desenzano del Garda (Brescia), Divisione di Chirurgia.
Chir Ital. 1988 Feb;40(1):77-82.
After briefly analyzing the concept and genesis of dysplasia starting with the normal large bowel cell and then illustrating the polyp-carcinoma sequence, the authors report on their experience with 283 endoscopic polypectomies in a total of 1.875 patients undergoing endoscopy of the rectum, sigmoid and large bowel since 1980. Forty-nine polyps presented severe dysplasia, and 38 had already degenerated to carcinoma; nine of the carcinomas had invaded the stalk and the patients were subjected to resection of the colon and mesocolon, lymph-node metastases being observed in 1 case.
作者首先从正常大肠细胞入手简要分析了发育异常的概念和成因，接着阐述了息肉 - 癌序列，之后报告了自1980年以来他们对1875例接受直肠、乙状结肠和大肠内镜检查患者进行283例内镜息肉切除术的经验。49枚息肉呈现重度发育异常，38枚已恶变为癌；其中9例癌侵犯了蒂部，这些患者接受了结肠和结肠系膜切除术，1例观察到有淋巴结转移。
