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Oesophageal atresia without major cardiovascular anomalies: Is management justified at a district paediatric surgical institution?食管闭锁无重大心血管异常:在地区儿科外科机构进行治疗是否合理?
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本文引用的文献

1
Management of long gap esophageal atresia: A systematic review and evidence-based guidelines from the APSA Outcomes and Evidence Based Practice Committee.长段食管闭锁的管理:来自美国小儿外科学会(APSA)结果与循证实践委员会的系统评价和循证指南
J Pediatr Surg. 2019 Apr;54(4):675-687. doi: 10.1016/j.jpedsurg.2018.12.019. Epub 2019 Feb 7.
2
The Visionaries, the Virtuosos, and the History of Congenital Esophageal Atresia Surgery.《先见之明者、技艺精湛者和先天性食管闭锁手术史》
Ann Thorac Surg. 2018 Jul;106(1):305-308. doi: 10.1016/j.athoracsur.2018.02.069. Epub 2018 Mar 31.
3
How to Care for Patients with EA-TEF: The Known and the Unknown.如何护理食管闭锁合并气管食管瘘患者:已知与未知
Curr Gastroenterol Rep. 2017 Nov 25;19(12):65. doi: 10.1007/s11894-017-0605-6.
4
Respiratory Morbidity in Children with Repaired Congenital Esophageal Atresia with or without Tracheoesophageal Fistula.先天性食管闭锁合并或不合并气管食管瘘修复术后儿童的呼吸道发病率
Int J Environ Res Public Health. 2017 Sep 27;14(10):1136. doi: 10.3390/ijerph14101136.
5
Anastomotic Strictures after Esophageal Atresia Repair: Incidence, Investigations, and Management, Including Treatment of Refractory and Recurrent Strictures.食管闭锁修复术后吻合口狭窄:发生率、检查及处理,包括难治性和复发性狭窄的治疗
Front Pediatr. 2017 May 29;5:120. doi: 10.3389/fped.2017.00120. eCollection 2017.
6
Dilations of anastomotic strictures over time after repair of esophageal atresia.食管闭锁修复术后吻合口狭窄随时间的扩张情况。
Pediatr Surg Int. 2017 Feb;33(2):191-195. doi: 10.1007/s00383-016-4013-z. Epub 2016 Nov 15.
7
ESPGHAN-NASPGHAN Guidelines for the Evaluation and Treatment of Gastrointestinal and Nutritional Complications in Children With Esophageal Atresia-Tracheoesophageal Fistula.欧洲儿科胃肠病、肝病和营养学会-北美儿科胃肠病、肝病和营养学会食管闭锁-气管食管瘘患儿胃肠道及营养并发症评估与治疗指南
J Pediatr Gastroenterol Nutr. 2016 Nov;63(5):550-570. doi: 10.1097/MPG.0000000000001401.
8
Management of oesophageal atresia in a developing country: Is primary repair forbidden?发展中国家食管闭锁的管理:一期修复是否被禁止?
Afr J Paediatr Surg. 2016 Jul-Sep;13(3):114-9. doi: 10.4103/0189-6725.187801.
9
Immediate primary anastomosis for isolated oesophageal atresia: A single-centre experience.孤立性食管闭锁的一期直接吻合术:单中心经验
Afr J Paediatr Surg. 2015 Oct-Dec;12(4):273-9. doi: 10.4103/0189-6725.172572.
10
Endoscopic Management of Anastomotic Esophageal Strictures Secondary to Esophageal Atresia.食管闭锁继发吻合口食管狭窄的内镜治疗
Gastrointest Endosc Clin N Am. 2016 Jan;26(1):201-19. doi: 10.1016/j.giec.2015.09.002.

食管闭锁无重大心血管异常:在地区儿科外科机构进行治疗是否合理?

Oesophageal atresia without major cardiovascular anomalies: Is management justified at a district paediatric surgical institution?

机构信息

Department of Paediatric Surgery, School of Medicine, University of Patras; Department of Paediatric Surgery, Patras Children's Hospital, Patras, Greece.

Department of Paediatric Surgery, Patras Children's Hospital, Patras, Greece.

出版信息

Afr J Paediatr Surg. 2021 Jan-Mar;18(1):58-61. doi: 10.4103/ajps.AJPS_113_20.

DOI:10.4103/ajps.AJPS_113_20
PMID:33595544
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8109746/
Abstract

BACKGROUND

Oesophageal atresia lacks sufficiently documented treatment approach, as guidelines are based rather on the opinion of experts than on systematic data. We aimed to answer the question if treatment of patients without major cardiovascular anomalies could be justified at a peripheral paediatric surgical institution, by evaluating the outcome of surgical correction.

METHODS

Thirty-three neonates underwent surgery for correction of oesophageal atresia during a period of 20 years. They were categorised into two time-period groups, to follow-up the evolution of surgical intervention and complications through time. Evaluation of post-operative outcome and morbidity was performed. The results were related to those of our recent cross-sectional study on families having experienced oesophageal atresia performed years after repair, regarding the long-term quality of life.

RESULTS

A shift from staged to primary repair occurred throughout time in the patients with a marginal long gap between proximal and distal oesophagus (P = 0.008). Anastomotic stenosis was the major short-term complication encountered, treated with post-operative dilation sessions. Dysphagia and reflux were the most common long-term complications.

CONCLUSIONS

Oesophageal atresia without severe cardiovascular abnormalities could be treated at a peripheral paediatric surgical department with satisfactory outcomes. However, qualified paediatric surgeons, anaesthesiologists and neonatologists and the availability of neonatal intensive care unit should be definitively required.

摘要

背景

食管闭锁缺乏充分记录的治疗方法,因为指南主要基于专家意见,而不是系统数据。我们旨在通过评估手术矫正的结果,回答在儿科外科机构治疗无重大心血管异常的患者是否合理的问题。

方法

在 20 年期间,33 名新生儿因食管闭锁接受了手术治疗。他们被分为两个时间组,以随着时间的推移跟踪手术干预和并发症的演变。评估了术后结果和发病率。将结果与我们最近的一项关于经历食管闭锁修复多年后家庭的横断面研究进行了比较,该研究涉及长期生活质量。

结果

近端和远端食管之间存在边缘长间隙的患者中,分期修复向一期修复转变(P = 0.008)。吻合口狭窄是最常见的短期并发症,采用术后扩张治疗。吞咽困难和反流是最常见的长期并发症。

结论

无严重心血管异常的食管闭锁可在儿科外科的周边部门治疗,效果满意。然而,需要有合格的儿科外科医生、麻醉师和新生儿科医生,以及新生儿重症监护病房的支持。