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机器人辅助与腹腔镜脾切除术治疗非创伤性脾脏疾病的系统评价和Meta分析

Robotic vs. Laparoscopic Splenectomy in Management of Non-traumatic Splenic Pathologies: A Systematic Review and Meta-Analysis.

作者信息

Bhattacharya Pratik, Phelan Liam, Fisher Simon, Hajibandeh Shahab, Hajibandeh Shahin

机构信息

Department of General Surgery, 1731Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.

Department of General Surgery, 156631Birmingham Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

出版信息

Am Surg. 2022 Jan;88(1):38-47. doi: 10.1177/0003134821995057. Epub 2021 Feb 17.

DOI:10.1177/0003134821995057
PMID:33596106
Abstract

We aimed to evaluate comparative outcomes of robotic and laparoscopic splenectomy in patients with non-traumatic splenic pathologies. A systematic search of electronic databases and bibliographic reference lists were conducted, and a combination of free text and controlled vocabulary search adapted to thesaurus headings, search operators and limits in electronic databases were applied. Intraoperative and post-operative complications, wound infection, haematoma, conversion to open procedure, return to theatre, volume of blood loss, procedure time and length of hospital stay were the evaluated outcome parameters. We identified 8 comparative studies reporting a total of 560 patients comparing outcomes of robotic ( = 202) and laparoscopic ( = 258) splenectomies. The robotic approach was associated with significantly lower volume of blood loss (MD: -82.53 mls, 95% CI -161.91 to -3.16, = .04) than the laparoscopic approach. There was no significant difference in intraoperative complications (OR: 0.68, 95% CI .21-2.01, = .51), post-operative complications (OR: .91, 95% CI .40-2.06, = .82), wound infection (RD: -.01, 95% CI -.04-.03, = .78), haematoma (OR: 0.40, 95% CI .04-4.03, = .44), conversion to open (OR: 0.63; 95% CI, .24-1.70, = .36), return to theatre (RD: -.04, 95% CI -.09-.02, = .16), procedure time (MD: 3.63; 95% CI -16.99-24.25, = .73) and length of hospital stay (MD: -.21; 95% CI -1.17 - .75, = .67) between 2 groups. In conclusion, robotic and laparoscopic splenectomies seem to have comparable perioperative outcomes with similar rate of conversion to an open procedure, procedure time and length of hospital stay. The former may potentially reduce the volume of intraoperative blood loss. Future higher level research is required to evaluate the cost-effectiveness and clinical outcomes.

摘要

我们旨在评估机器人辅助脾切除术和腹腔镜脾切除术治疗非创伤性脾脏疾病患者的比较结果。我们对电子数据库和文献参考列表进行了系统检索,并采用了适用于电子数据库中叙词表标题、检索运算符和限制的自由文本与受控词汇搜索相结合的方法。术中及术后并发症、伤口感染、血肿、转为开放手术、返回手术室、失血量、手术时间和住院时间是评估的结果参数。我们确定了8项比较研究,共报告了560例患者,比较了机器人辅助脾切除术(n = 202)和腹腔镜脾切除术(n = 258)的结果。与腹腔镜手术相比,机器人手术的失血量显著更低(MD:-82.53毫升,95%CI -161.91至-3.16,P = 0.04)。两组在术中并发症(OR:0.68,95%CI 0.21 - 2.01,P = 0.51)、术后并发症(OR:0.91,95%CI 0.40 - 2.06,P = 0.82)、伤口感染(RD:-0.01,95%CI -0.04 - 0.03,P = 0.78)、血肿(OR:0.40,95%CI 0.04 - 4.03,P = 0.44)、转为开放手术(OR:0.63;95%CI,0.24 - 1.70,P = 0.36)、返回手术室(RD:-0.04,95%CI -0.09 - 0.02,P = 0.16)、手术时间(MD:3.63;95%CI -16.99 - 24.25,P = 0.73)和住院时间(MD:-0.21;95%CI -1.17 - 0.75,P = 0.67)方面均无显著差异。总之,机器人辅助脾切除术和腹腔镜脾切除术的围手术期结果似乎相当,转为开放手术的比例、手术时间和住院时间相似。前者可能会减少术中失血量。未来需要更高水平的研究来评估成本效益和临床结果。

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