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On Bugs and Blowholes: Why Is Aspiration the Rule, Not the Exception?

作者信息

Mac Aogáin Micheál, Baker Jennifer M, Dickson Robert P

机构信息

Department of Biochemistry St. James's Hospital Dublin, Ireland.

School of Medicine Trinity College Dublin Dublin, Ireland.

出版信息

Am J Respir Crit Care Med. 2021 May 1;203(9):1049-1051. doi: 10.1164/rccm.202011-4257ED.

DOI:10.1164/rccm.202011-4257ED
PMID:33596387
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8314891/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e171/8314891/97a5e83ea4fd/rccm.202011-4257EDf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e171/8314891/97a5e83ea4fd/rccm.202011-4257EDf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e171/8314891/97a5e83ea4fd/rccm.202011-4257EDf1.jpg

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Episodic Aspiration with Oral Commensals Induces a MyD88-dependent, Pulmonary T-Helper Cell Type 17 Response that Mitigates Susceptibility to .伴有口腔共生菌的间歇性误吸会引发一种依赖MyD88的肺部17型辅助性T细胞反应，该反应可减轻对……的易感性。
Am J Respir Crit Care Med. 2021 May 1;203(9):1099-1111. doi: 10.1164/rccm.202005-1596OC.
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Lung CD4 resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia.肺脏 CD4 固有记忆 T 细胞重塑上皮细胞反应，在肺炎期间加速中性粒细胞募集。
Mucosal Immunol. 2020 Mar;13(2):334-343. doi: 10.1038/s41385-019-0229-2. Epub 2019 Nov 20.
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Distinct "Immunoallertypes" of Disease and High Frequencies of Sensitization in Non-Cystic Fibrosis Bronchiectasis.
重症吸入性肺炎中的上、下呼吸道微生物群
iScience. 2023 May 6;26(6):106832. doi: 10.1016/j.isci.2023.106832. eCollection 2023 Jun 16.
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Microbial Dysregulation of the Gut-Lung Axis in Bronchiectasis.支气管扩张症中肠道-肺部轴的微生物失调。
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Whole lung tissue is the preferred sampling method for amplicon-based characterization of murine lung microbiota.全肺组织是基于扩增子的鼠肺微生物组特征分析的首选采样方法。
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