Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Max Planck Institute for Human Development, 14195 Berlin, Germany; Center for Lifespan Psychology, Max Planck Institute for Human Development, 14195 Berlin, Germany.
Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Max Planck Institute for Human Development, 14195 Berlin, Germany; Center for Lifespan Psychology, Max Planck Institute for Human Development, 14195 Berlin, Germany.
Neuron. 2021 Mar 3;109(5):751-766. doi: 10.1016/j.neuron.2021.01.023. Epub 2021 Feb 16.
Human and non-human animal behavior is highly malleable and adapts successfully to internal and external demands. Such behavioral success stands in striking contrast to the apparent instability in neural activity (i.e., variability) from which it arises. Here, we summon the considerable evidence across scales, species, and imaging modalities that neural variability represents a key, undervalued dimension for understanding brain-behavior relationships at inter- and intra-individual levels. We believe that only by incorporating a specific focus on variability will the neural foundation of behavior be comprehensively understood.
人类和非人类动物的行为具有高度的可塑性，并能成功适应内部和外部的需求。这种行为上的成功与神经活动（即变异性）的明显不稳定性形成鲜明对比。在这里，我们汇集了来自不同尺度、物种和成像模态的大量证据，表明神经变异性是理解个体间和个体内脑-行为关系的一个关键但被低估的维度。我们相信，只有通过特别关注变异性，才能全面理解行为的神经基础。
