Glikmann G, Petersen I, Mordhorst C H
Ornithosis Department, Statens Seruminstitut, Copenhagen, Denmark.
Dan Med Bull. 1988 Apr;35(2):185-7.
The prevalence of mumps and measles IgG antibodies in a randomly selected population of children was determined by an enzyme-linked immunosorbent assay (ELISA) before routine measles-mumps-rubella (MMR) vaccination was introduced in Denmark. Testing of sera from about 2,520 Danish children between one and 17 years of age showed that mumps antibodies were acquired at an early age. The peak acquisition rate was between the ages of four and five; before the age of 15, 90% of children had antibodies to mumps. Immunity to measles occurred at an even earlier age; more than 50% of four-year-old and nearly all (98%) nine-year-old children had IgG antibodies to measles virus. The study showed that about 10% of the young adult Danish population was still susceptible to mumps infection whereas only about 1% of individuals at age 17 had not acquired immunity to measles virus.
在丹麦引入常规麻疹-腮腺炎-风疹（MMR）疫苗接种之前，通过酶联免疫吸附测定（ELISA）确定了随机抽取的儿童群体中腮腺炎和麻疹IgG抗体的流行情况。对约2520名1至17岁丹麦儿童的血清检测表明，腮腺炎抗体在儿童早期即可获得。抗体获得率的峰值出现在4至5岁之间；15岁之前，90%的儿童拥有腮腺炎抗体。对麻疹的免疫力在更早的年龄就已出现；超过50%的4岁儿童以及几乎所有（98%）的9岁儿童都拥有针对麻疹病毒的IgG抗体。该研究表明，约10%的丹麦年轻成年人仍易感染腮腺炎，而17岁的个体中只有约1%尚未获得对麻疹病毒的免疫力。
