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流感相关性脑病中的新发癫痫持续状态:遗传性全身性癫痫的表现形式。

New onset status epilepticus in influenza associated encephalopathy: The presenting manifestation of genetic generalized epilepsy.

作者信息

Giovannini G, Turchi G, Mazzoli M, Vaudano A E, Meletti S

机构信息

Neurology Unit, OCB Hospital, Azienda Ospedaliero-Universitaria, Modena, Italy.

PhD Program in Clinical and Experimental Medicine, University of Modena and Reggio Emilia, Modena, Italy.

出版信息

Epilepsy Behav Rep. 2020 Nov 25;16:100413. doi: 10.1016/j.ebr.2020.100413. eCollection 2021.

DOI:10.1016/j.ebr.2020.100413
PMID:33598653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7868800/
Abstract

We hereby present a case of a young woman with no history of seizures or epilepsy who experienced a de novo generalized Non Convulsive Status Epilepticus (NCSE) followed by encephalopathy lasting for several days during influenza B infection. Influenza can have a broad spectrum of presentation ranging from an uncomplicated illness to many serious conditions as is the case of influenza associated encephalitis/encephalopathy (IAE). In this context however, it is possible to observe seizures and/or status epilepticus as the presenting manifestation of a genetic generalized epilepsy.

摘要

我们在此报告一例年轻女性病例,该患者既往无癫痫发作或癫痫病史,在感染乙型流感期间出现了新发的全身性非惊厥性癫痫持续状态(NCSE),随后出现了持续数天的脑病。流感的表现形式多种多样,从简单的疾病到许多严重病症,如流感相关脑炎/脑病(IAE)。然而,在这种情况下,有可能观察到癫痫发作和/或癫痫持续状态作为遗传性全身性癫痫的首发表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/294a/7868800/a5917d73ad7b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/294a/7868800/a5917d73ad7b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/294a/7868800/a5917d73ad7b/gr1.jpg

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本文引用的文献

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Recommendations for the use of structural magnetic resonance imaging in the care of patients with epilepsy: A consensus report from the International League Against Epilepsy Neuroimaging Task Force.推荐使用结构磁共振成像技术于癫痫患者的临床诊疗:国际抗癫痫联盟神经影像学工作组的共识报告。
Epilepsia. 2019 Jun;60(6):1054-1068. doi: 10.1111/epi.15612. Epub 2019 May 28.
2
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Epileptic Disord. 2018 Dec 1;20(6):502-507. doi: 10.1684/epd.2018.1008.
3
Influenza B-related meningoencephalitis in adults.
成人乙型流感相关性脑膜脑炎
BMJ Case Rep. 2018 Jun 21;2018:bcr-2018-224960. doi: 10.1136/bcr-2018-224960.
4
Kleine-Levin syndrome elicited by encephalopathy with reversible splenial lesion.伴有可逆性胼胝体压部病变的脑病引发的克莱恩-莱文综合征
Pediatr Int. 2017 Aug;59(8):929-931. doi: 10.1111/ped.13326.
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Salzburg Consensus Criteria for Non-Convulsive Status Epilepticus--approach to clinical application.非惊厥性癫痫持续状态的萨尔茨堡共识标准——临床应用方法
Epilepsy Behav. 2015 Aug;49:158-63. doi: 10.1016/j.yebeh.2015.05.007. Epub 2015 Jun 17.
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Mild encephalopathy with reversible splenial lesion: an important differential of encephalitis.伴有可逆性胼胝体压部病变的轻度脑病:脑炎的重要鉴别诊断
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