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纽约市感染SARS-CoV-2的住院患者的COVID-19康复计划的结果:一项前瞻性队列研究。

Outcomes of a COVID-19 recovery program for patients hospitalized with SARS-CoV-2 infection in New York City: A prospective cohort study.

作者信息

Hameed Farah, Palatulan Eugene, Jaywant Abhishek, Said Rami, Lau Corinna, Sood Vandana, Layton Aimee, Gellhorn Alfred

机构信息

Department of Rehabilitation and Regenerative Medicine, Columbia University Irving Medical Center, New York, New York, USA.

Department of Rehabilitation Medicine, Weill Cornell Medicine, New York, New York, USA.

出版信息

PM R. 2021 Jun;13(6):609-617. doi: 10.1002/pmrj.12578. Epub 2021 Mar 22.

Abstract

BACKGROUND

In the spring of 2020, New York City was an epicenter of coronavirus disease 2019 (COVID-19). The post-hospitalization needs of COVID-19 patients were not understood and no outpatient rehabilitation programs had been described.

OBJECTIVE

To evaluate whether a virtual rehabilitation program would lead to improvements in strength and cardiopulmonary endurance when compared with no intervention in patients discharged home with persistent COVID-19 symptoms.

DESIGN

Prospective cohort study.

SETTING

Academic medical center.

PATIENTS

Between April and July 2020, 106 patients discharged home with persistent COVID-19 symptoms were treated. Forty-four patients performed virtual physical therapy (VPT); 25 patients performed home physical therapy (HPT); 17 patients performed independent exercise program (IE); and 20 patients did not perform therapy.

INTERVENTIONS

All patients were assessed by physiatry. VPT sessions were delivered via secure Health Insurance Portability and Accountability Act compliant telehealth platform 1-2 times/week. Patients were asked to follow up 2 weeks after initial evaluation.

MAIN OUTCOME MEASURES

Primary study outcome measures were the change in lower body strength, measured by the 30-second sit-to-stand test; and the change in cardiopulmonary endurance, measured by the 2-minute step test.

RESULTS

At the time of follow-up, 65% of patients in the VPT group and 88% of patients in the HPT group met the clinically meaningful difference for improvement in sit-to-stand scores, compared with 50% and 17% of those in the IE group and no-exercise group (P = .056). The clinically meaningful difference for improvement in the step test was met by 74% of patients in the VPT group and 50% of patients in the HPT, IE, and no-exercise groups (P = .12).

CONCLUSIONS

Virtual outpatient rehabilitation for patients recovering from COVID-19 improved lower limb strength and cardiopulmonary endurance, and an HPT program improved lower limb strength. Virtual rehabilitation seems to be an efficacious method of treatment delivery for recovering COVID-19 patients.

摘要

背景

2020年春季,纽约市是2019冠状病毒病(COVID-19)的疫情中心。COVID-19患者出院后的需求尚不明确,且尚无门诊康复项目的相关描述。

目的

评估与未接受干预的持续有COVID-19症状且出院回家的患者相比,虚拟康复项目是否能改善患者的力量和心肺耐力。

设计

前瞻性队列研究。

地点

学术医疗中心。

患者

2020年4月至7月期间,106例持续有COVID-19症状且出院回家的患者接受了治疗。44例患者进行了虚拟物理治疗(VPT);25例患者进行了家庭物理治疗(HPT);17例患者进行了独立锻炼项目(IE);20例患者未接受治疗。

干预措施

所有患者均接受了物理医学与康复科的评估。VPT课程通过符合《健康保险流通与责任法案》要求的安全远程医疗平台每周进行1 - 2次。患者被要求在初次评估后2周进行随访。

主要结局指标

主要研究结局指标包括通过30秒坐立试验测量的下肢力量变化;以及通过2分钟踏步试验测量的心肺耐力变化。

结果

在随访时,VPT组65%的患者和HPT组88%的患者在坐立试验得分改善方面达到了具有临床意义的差异,而IE组和无运动组分别为50%和17%(P = 0.056)。VPT组74%的患者在踏步试验改善方面达到了具有临床意义的差异,HPT组、IE组和无运动组分别为50%(P = 0.12)。

结论

COVID-19康复患者的虚拟门诊康复改善了下肢力量和心肺耐力,HPT项目改善了下肢力量。虚拟康复似乎是COVID-19康复患者有效的治疗方式。

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