OM Research Centre, SA-17/3, P-4, Sri Krishna Nagar, Paharia Ghazipur Road, Varanasi, 221002, Uttar Pradesh, India.
M V Hospital and Research Centre, 314/30 Mirza Mandi, Post Office, Chowk, Lucknow, 226003, Uttar Pradesh, India.
J Ethnopharmacol. 2021 May 23;272:113929. doi: 10.1016/j.jep.2021.113929. Epub 2021 Feb 15.
Ashwagandha is a reputed herb in traditional Ayurveda, used for various ailments and improving general well-being. Improved cardiorespiratory endurance can aid in attaining better physiological, metabolic, and functional abilities in humans. According to Ayurveda, Ashwagandha has such potential to improve human health.
This study aimed to evaluate the efficacy and safety of Ashwagandha root extract in enhancing cardiorespiratory endurance in healthy athletic adults.
Fifty healthy athletic adults were selected randomly and equally allocated to Ashwagandha and placebo groups. The Ashwagandha group received 300 mg of Ashwagandha root extract capsules, twice daily, for 8-weeks. Cardiorespiratory endurance was assessed by measuring the maximum aerobic capacity (VO2 max). Estimation of stress management was done through Total Quality Recovery Scores (TQR), Recovery-Stress Questionnaire for Athletes (RESTQ), and Daily Analysis of Life Demands for Athletes (DALDA) questionnaires along with the antioxidant level measurement.
At the end of the study, a statistically significant improvement in VO2 max outcome was observed in the Ashwagandha group when compared to the placebo group (P = 0.0074). The subjects in the Ashwagandha group also displayed a statistically significant increase at the end of the study when compared to the baseline (P < 0.0001). Significantly improved TQR scores were observed in the Ashwagandha group members compared to their placebo counterparts (P < 0.0001). DALDA questionnaire analysis in the Ashwagandha group was found statistically significant (P < 0.0001) compared to the placebo group. RESTQ assessment also yielded better outcomes, especially for fatigue recovery (P < 0.0001), lack of energy (P < 0.0001), and fitness analysis (P < 0.0001). The enhanced antioxidant level was significant (P < 0.0001) in the Ashwagandha group.
The present findings suggest that Ashwagandha root extract can successfully enhance cardiorespiratory endurance and improve the quality of life in healthy athletic adults. No adverse events were reported by any of the subjects in this study.
在传统阿育吠陀医学中，南非醉茄是一种备受推崇的草药，用于治疗各种疾病并改善整体健康状况。提高心肺耐力有助于提高人类在生理、代谢和功能方面的能力。根据阿育吠陀医学，南非醉茄具有改善人类健康的潜力。
本研究旨在评估南非醉茄根提取物在增强健康运动员心肺耐力方面的功效和安全性。
随机选择 50 名健康的运动员，并将他们平均分配到南非醉茄组和安慰剂组。南非醉茄组每天服用 300 毫克南非醉茄根提取物胶囊，每日两次，持续 8 周。心肺耐力通过测量最大有氧能力（VO2 max）来评估。通过总质量恢复评分（TQR）、运动员恢复压力问卷（RESTQ）和运动员每日生活需求分析（DALDA）问卷以及抗氧化剂水平测量来评估压力管理的效果。
研究结束时，与安慰剂组相比，南非醉茄组的 VO2 max 结果有统计学意义的改善（P=0.0074）。与基线相比，南非醉茄组的研究结束时也显示出统计学意义的增加（P<0.0001）。与安慰剂组相比，南非醉茄组的 TQR 评分显著提高（P<0.0001）。与安慰剂组相比，南非醉茄组的 DALDA 问卷分析具有统计学意义（P<0.0001）。RESTQ 评估也产生了更好的结果，特别是在疲劳恢复方面（P<0.0001）、缺乏能量方面（P<0.0001）和健身分析方面（P<0.0001）。南非醉茄组的抗氧化剂水平显著提高（P<0.0001）。
本研究结果表明，南非醉茄根提取物可成功增强健康运动员的心肺耐力并提高其生活质量。本研究中没有受试者报告出现不良反应。
