孤立性双侧先天性泪腺发育不全——病例系列。

Isolated bilateral congenital lacrimal gland agenesis-a case series.

机构信息

Faculty of Medicine, Department of Medicine, McGill University, Montreal, Quebec, Canada.

Department of Ophthalmology & Vision Science, UC Davis Eye Center, California.

出版信息

J AAPOS. 2021 Apr;25(2):109-112.e1. doi: 10.1016/j.jaapos.2020.11.008. Epub 2021 Feb 16.

DOI:10.1016/j.jaapos.2020.11.008

PMID:33601047

Abstract

We report 2 pediatric cases of isolated bilateral congenital lacrimal gland agenesis (CLGA). Patient 1 (1 year of age) and patient 2 (2 years of age) presented with symptoms of alacrimia and were diagnosed with bilateral isolated CLGA based on magnetic resonance imaging. Both patients were otherwise healthy, with no systemic associations. Molecular analysis for genetic causes of CLGA were negative. Both have been successfully medically managed.

摘要

我们报告了 2 例儿童孤立性双侧先天性泪腺发育不全（CLGA）病例。患者 1（1 岁）和患者 2（2 岁）表现出无泪症状，根据磁共振成像诊断为双侧孤立性 CLGA。两名患者均身体健康，无全身相关疾病。CLGA 的遗传原因的分子分析均为阴性。两名患者均成功接受了药物治疗。