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中国失独父母创伤后应激障碍的患病率及影响因素:系统评价和荟萃分析。

Prevalence and risk factors of posttraumatic stress disorder among Chinese shidu parents: A systemic review and meta-analysis.

机构信息

Centre for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.

Centre for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, China; NHC Key Lab of Health Economics and Policy Research (Shandong University), Jinan 250012, China.

出版信息

J Affect Disord. 2021 Mar 1;282:1180-1186. doi: 10.1016/j.jad.2021.01.017. Epub 2021 Jan 13.

DOI:10.1016/j.jad.2021.01.017
PMID:33601693
Abstract

BACKGROUND

Losing the only child is an extremely distressful life event for parents. Previous studies indicated that shidu parents were more vulnerable to develop posttraumatic stress disorder (PTSD). This study aims to calculate the pooled prevalence of PTSD and identify its risk factors.

METHOD

We conducted a systematic literature search in PubMed, Web of Science, Embase, China National Knowledge Infrastructure (CNKI), Wanfang databases, Vip databases. We performed a meta-analysis using random effects models to calculate the pooled PTSD in shidu parents. Associated factors for PTSD was evaluated by determining standardized mean difference (SMD) with 95% CIs. All analyses were performed using the Stata 16.0.

RESULTS

Eight articles (covering 2,722 shidu parents) were included in this study. The pooled prevalence of PTSD was 46.8% (95%CI: 33.2%-60.3%) among Chinese shidu parents. Female (SMD[95%CI]: 0.41[0.20, 0.62]), higher education level (SMD[95%CI]: 0.15[0.03, 0.28]), lower income (SMD[95%CI]: 0.33[0.13, 0.53]), losing a daughter (SMD[95%CI]: 0.16[0.03, 0.28]) and shorter time since loss (SMD[95%CI]: 0.24[0.07, 0.40]) were significantly associated with a higher PTSD prevalence. Registered residence, cause of death, age of the child, and having a grandchild were not associated with PTSD.

LIMITATIONS

Some variables included in this meta-analysis were only measured twice, which limited the conclusions to some extent.

CONCLUSION

This meta-analysis indicated that nearly half of shidu parents experienced PTSD and provided evidence of risk factors for PTSD in shidu parents. Further research is suggested to determine how these factors interact. Effective interventions should be conducted to shidu parents with PTSD.

摘要

背景

失去独生子/女对父母来说是一场极其痛苦的生活事件。先前的研究表明,失独父母更容易患上创伤后应激障碍(PTSD)。本研究旨在计算 PTSD 的总患病率,并确定其危险因素。

方法

我们在 PubMed、Web of Science、Embase、中国知网(CNKI)、万方数据库、维普数据库中进行了系统文献检索。我们使用随机效应模型进行荟萃分析,以计算失独父母的 PTSD 总患病率。使用标准化均数差(SMD)和 95%置信区间(CI)来评估 PTSD 的相关因素。所有分析均使用 Stata 16.0 进行。

结果

本研究纳入了 8 篇文章(涵盖 2722 名失独父母)。中国失独父母 PTSD 的总患病率为 46.8%(95%CI:33.2%-60.3%)。女性(SMD[95%CI]:0.41[0.20, 0.62])、较高的教育水平(SMD[95%CI]:0.15[0.03, 0.28])、较低的收入(SMD[95%CI]:0.33[0.13, 0.53])、失去女儿(SMD[95%CI]:0.16[0.03, 0.28])和失去孩子后较短的时间(SMD[95%CI]:0.24[0.07, 0.40])与 PTSD 患病率较高显著相关。户籍、死因、子女年龄和是否有孙辈与 PTSD 无关。

局限性

本荟萃分析中纳入的一些变量仅测量了两次,这在一定程度上限制了结论。

结论

本荟萃分析表明,近一半的失独父母经历了 PTSD,并为失独父母 PTSD 的危险因素提供了证据。建议进一步研究这些因素如何相互作用。应对有 PTSD 的失独父母进行有效的干预。

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