Chapdelaine Alexandra, Lamoureux-Lamarche Catherine, Poder Thomas G, Vasiliadis Helen-Maria
PRIMUS Research Group, Faculty of Medicine & Health Sciences, Université de Sherbrooke, QC, Canada.
Faculty of Medicine & Health Sciences, Université de Sherbrooke, QC, Canada.
Pharmacogenomics. 2021 Feb;22(3):125-135. doi: 10.2217/pgs-2020-0077. Epub 2021 Feb 19.
To assess the impact of sociodemographic factors and beliefs about medicines on the uptake of pharmacogenomic testing in older adults in a public healthcare system. Data are based on a sample of 347 primary care older adults. Most respondents (90%) were willing to provide a saliva sample and 47% were willing to pay for it. Increased age (odds ratio: 0.91; p = 0.04) and negative beliefs about the harmfulness of medicines (odds ratio: 0.68; p = 0.02) were associated with a decreased willingness to provide a sample. Lower education (less than university, odds ratio: 0.54; p = 0.04) was associated with a decreased willingness to pay. Education and beliefs about medicines are important factors in the acceptability of pharmacogenomic testing in older adults.
评估社会人口学因素和对药物的认知对公共医疗系统中老年人药物基因组检测接受度的影响。数据基于347名初级保健老年人的样本。大多数受访者（90%）愿意提供唾液样本，47%愿意为此付费。年龄增长（优势比：0.91；p = 0.04）和对药物有害性的负面认知（优势比：0.68；p = 0.02）与提供样本的意愿降低相关。教育程度较低（低于大学学历，优势比：0.54；p = 0.04）与付费意愿降低相关。教育程度和对药物的认知是影响老年人对药物基因组检测接受度的重要因素。
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