Li Hai-Xin, Gao Cai-Jie, Cheng Shan, Mao Zhi-Lei, Wang Huai-Yan
Department of Child Healthcare, Changzhou Women and Children Health Care Hospital, Changzhou, Jiangsu 213000, P.R. China.
Department of Infectious Disease, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210008, P.R. China.
Exp Ther Med. 2021 Mar;21(3):237. doi: 10.3892/etm.2021.9668. Epub 2021 Jan 21.
Premature infants are prone to dyspnea after birth due to immature development, and some infants require respiratory assistance. However, the risk factors for respiratory assistance in premature infants are rarely reported. The present study enrolled 3,394 premature infants (665 infants had been provided with respiratory assistance and 2,729 had not used respiratory assistance) to retrospectively analyze the risk factors associated with respiratory aid. The multivariate logistic regression analysis demonstrated that placental abnormality [odds ratio (OR)=1.284; P=0.048], the male sex (OR=0.696; P=0.001), delivery via cesarean section (OR=1.538; P<0.001), low 1-min Apgar score (OR=0.727; P<0.001), low birth weight (OR=0.999; P=0.005) and low gestational age (OR=0.616; P<0.001) were independent risk factors for respiratory assistance in premature infants. Overall, a number of risk factors, including placental abnormality, cesarean section, low 1-min Apgar score, low birth weight and small gestational age, were identified for respiratory assistance in premature infants. By conducting a risk assessment of risk factors at birth and using this information to provide timely respiratory assistance, the survival rates of premature infants may increase.
早产儿由于发育不成熟,出生后易出现呼吸困难,部分婴儿需要呼吸支持。然而,关于早产儿呼吸支持的危险因素鲜有报道。本研究纳入了3394例早产儿(665例接受了呼吸支持,2729例未接受呼吸支持),回顾性分析与呼吸支持相关的危险因素。多因素logistic回归分析显示,胎盘异常[比值比(OR)=1.284;P=0.048]、男性(OR=0.696;P=0.001)、剖宫产分娩(OR=1.538;P<0.001)、1分钟Apgar评分低(OR=0.727;P<0.001)、低出生体重(OR=0.999;P=0.005)和低胎龄(OR=0.616;P<0.001)是早产儿呼吸支持的独立危险因素。总体而言,确定了一些与早产儿呼吸支持相关的危险因素,包括胎盘异常、剖宫产、1分钟Apgar评分低、低出生体重和小胎龄。通过对出生时的危险因素进行风险评估,并利用这些信息及时提供呼吸支持,可能会提高早产儿的存活率。