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肥胖症手术后不到 1 年怀孕:真的安全吗?

Pregnancy Less Than 1 Year After the Bariatric Surgery: Is It Really Safe?

机构信息

Department of Surgery, Advanced Laparoscopic Minimally Invasive and Bariatric Surgery Fellowship, Isfahan Minimally Invasive Surgery and Obesity Research Center, Alzahra University Hospital, Isfahan University of Medical Sciences, Sofe Blvd., Isfahan, Iran.

Department of Surgery, Advanced Laparoscopic Minimally Invasive and Bariatric Surgery Fellowship, Isfahan Minimally Invasive Surgery and Obesity Research Center, Amin University Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Obes Surg. 2021 May;31(5):2211-2218. doi: 10.1007/s11695-021-05260-w. Epub 2021 Feb 18.

Abstract

PURPOSE

The time interval between bariatric surgery and pregnancy is controversial. In this study, we report and compare the outcomes of pregnancy from two groups of bariatric surgery (BS) patients who became pregnant less than 12 months (early) and above 12 months (late) after surgery.

MATERIALS AND METHODS

For this retrospective study, women of reproductive age who became pregnant after BS between 2010 and 2019 were reviewed, allocated into two groups, and compared. Perinatal care was provided as standards and continued at monthly intervals by a gynecologist. Demographic data, pregnancy-related events, results of any screening tests in each trimester, the reports of all ultrasonographies, and lab data were extracted from their medical documents. Chi-square and t-test were used for analysis.

RESULTS

Four hundred seventy-seven out of 1046 participants were of reproductive age. 12 and 37 women were put in early and late pregnancy groups, respectively. No significant difference was observed in the rate of maternal complications, outcomes of pregnancies, and the rate of fetal and neonatal problems in pregnancies conceived during the first vs. second year postbariatric surgery. 91.6% of the patients with early pregnancy had at least one perinatal/neonatal finding. Mean neonatal birth weight was 2610 ± 152 and 2881 ± 315 g in early and late pregnancy groups, respectively. Patients with early pregnancy were not at significantly higher odds for any pregnancy-related or neonatal complications.

CONCLUSION

The rate of maternal, fetal, and neonatal complications in pregnancies conceived during the first vs. second postbariatric year were indifferent.

摘要

目的

肥胖症手术与妊娠之间的时间间隔存在争议。本研究报告并比较了两组肥胖症手术(BS)患者的妊娠结局,这两组患者在手术后 12 个月(早期)内和 12 个月以上(晚期)怀孕。

材料和方法

这项回顾性研究回顾了 2010 年至 2019 年接受 BS 后怀孕的育龄妇女,将其分为两组并进行比较。围产期护理按照标准进行,并由妇科医生每月进行一次。从她们的医疗记录中提取人口统计学数据、妊娠相关事件、每个三个月筛查试验的结果、所有超声报告以及实验室数据。使用卡方检验和 t 检验进行分析。

结果

在 1046 名参与者中,有 477 名是育龄妇女。12 名和 37 名女性分别归入早期和晚期妊娠组。在母亲并发症的发生率、妊娠结局以及在 BS 后第一年与第二年怀孕的胎儿和新生儿问题的发生率方面,两组之间没有观察到显著差异。91.6%的早期妊娠患者至少有一次围产期/新生儿发现。早期和晚期妊娠组新生儿的平均出生体重分别为 2610±152g 和 2881±315g。早期妊娠的患者在任何妊娠相关或新生儿并发症方面的风险均无显著增加。

结论

在 BS 后第一年与第二年怀孕的母亲、胎儿和新生儿并发症的发生率无差异。

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