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胸腔镜辅助下胸腺切除术的全国应用及短期疗效。

National Use and Short-term Outcomes of Video and Robot-Assisted Thoracoscopic Thymectomies.

机构信息

David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California.

Division of Cardiac Surgery, University of California, Los Angeles, Los Angeles, California.

出版信息

Ann Thorac Surg. 2022 Jan;113(1):230-236. doi: 10.1016/j.athoracsur.2021.02.003. Epub 2021 Feb 16.

Abstract

BACKGROUND

Transsternal open thymectomy has long been the most widely used approach for thymectomy, but recent decades have seen the introduction of minimally invasive surgery (MIS), such as video-assisted thoracoscopic surgery (VATS) and robot-assisted thoracoscopic surgery (RATS) thymectomy. This retrospective cohort study provides a national comparison of trends, outcomes, and resource utilization of open, VATS, and RATS thymectomy.

METHODS

Admissions for thymectomies from 2008 to 2014 were identified in the National Inpatient Sample. Patients were identified as undergoing open, VATS, or RATS thymectomy. Propensity score-matched analyses were used to compare overall complication rates, length of stay (LOS), and cost of VATS and RATS thymectomies.

RESULTS

An estimated 23,087 patients underwent thymectomy during the study period: open in 16,025 (69%) and MIS in 7217 (31%). Of the MIS cohort, 4119 (18%) underwent VATS and 3097 (13%) underwent RATS. Performance of RATS and VATS thymectomy increased while that of open thymectomy declined. Baseline characteristics between VATS and RATS were similar, except more women underwent VATS thymectomy. No differences in LOS or overall complication rates were appreciable in this study. VATS was associated with the lowest cost of the 3 approaches.

CONCLUSIONS

Our findings demonstrate the increasing adoption of MIS and declining use of the open surgical approach for thymectomy. There are no differences in overall complication rates between RATS and VATS thymectomy, but RATS is associated with greater cost and lower cardiac complication rates.

摘要

背景

经胸骨正中切开胸腺切除术长期以来一直是胸腺切除术最广泛应用的方法,但近几十年来,微创外科(MIS),如电视辅助胸腔镜手术(VATS)和机器人辅助胸腔镜手术(RATS)胸腺切除术已经问世。这项回顾性队列研究提供了全国范围内对开放式、VATS 和 RATS 胸腺切除术的趋势、结果和资源利用的比较。

方法

从 2008 年到 2014 年,在全国住院患者样本中确定了胸腺切除术的入院人数。患者被确定为接受开放式、VATS 或 RATS 胸腺切除术。使用倾向评分匹配分析比较 VATS 和 RATS 胸腺切除术的总体并发症发生率、住院时间(LOS)和成本。

结果

在研究期间,估计有 23087 名患者接受了胸腺切除术:开放手术 16025 例(69%),MIS 7217 例(31%)。在 MIS 队列中,4119 例(18%)接受了 VATS 手术,3097 例(13%)接受了 RATS 手术。RATS 和 VATS 胸腺切除术的实施率增加,而开放式胸腺切除术的实施率下降。在这项研究中,VATS 和 RATS 之间的基线特征相似,只是更多的女性接受了 VATS 胸腺切除术。在 LOS 或总体并发症发生率方面,没有明显差异。3 种方法中,VATS 与最低成本相关。

结论

我们的研究结果表明,MIS 的采用越来越多,而开放式手术方法用于胸腺切除术的比例下降。RATS 和 VATS 胸腺切除术在总体并发症发生率方面没有差异,但 RATS 与更高的成本和更低的心脏并发症发生率相关。

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