Lee Ki Young, Lee Jung-Hee, Kang Kyung-Chung, Im Sang-Kyu, Lim Hae Seong, Choi Sun Whan
J Neurosurg Spine. 2021 Feb 19;34(5):706-715. doi: 10.3171/2020.8.SPINE201037. Print 2021 May 1.
Restoring the proper sagittal alignment in adult spinal deformity (ASD) can improve radiological and clinical outcomes, but pseudarthrosis including rod fracture (RF) is a common problematic complication. The purpose of this study was to analyze the methods for reducing the incidence of RF in deformity correction of ASD.
The authors retrospectively selected 178 consecutive patients (mean age 70.8 years) with lumbar degenerative kyphosis (LDK) who underwent deformity correction with a minimum 2-year follow-up. Patients were classified into the non-RF group (n = 131) and the RF group (n = 47). For predicting the crucial factors of RF, patient factors, radiographic parameters, and surgical factors were analyzed.
The overall incidence of RF was 26% (47/178 cases), occurring in 42% (42/100 cases) of pedicle subtraction osteotomy (PSO), 7% (5/67 cases) of lateral lumbar interbody fusion (LLIF) with posterior column osteotomy, 18% (23/129 cases) of cobalt chrome rods, 49% (24/49 cases) of titanium alloy rods, 6% (2/36 cases) placed with the accessory rod technique, and 32% (45/142 cases) placed with the 2-rod technique. There were no significant differences in the incidence of RF regarding patient factors between two groups. While both groups showed severe sagittal imbalance before operation, lumbar lordosis (LL) was more kyphotic and pelvic incidence (PI) minus LL (PI-LL) mismatch was greater in the RF group (p < 0.05). Postoperatively, while LL and PI-LL did not show significant differences between the two groups, LL and sagittal vertical axis correction were greater in the RF group (p < 0.05). Nonetheless, at the last follow-up, the two groups did not show significant differences in radiographic parameters except thoracolumbar junctional angles. As for surgical factors, use of the cobalt chrome rod and the accessory rod technique was significantly greater in the non-RF group (p < 0.05). As for the correction method, PSO was associated with more RFs than the other correction methods, including LLIF (p < 0.05). By logistic regression analysis, PSO, preoperative PI-LL mismatch, and the accessory rod technique were crucial factors for RF.
Greater preoperative sagittal spinopelvic malalignment including preoperative PI-LL mismatch was the crucial risk factor for RF in LDK patients 65 years or older. For restoring and maintaining sagittal alignment, use of the cobalt chrome rod, accessory rod technique, or LLIF was shown to be effective for reducing RF in ASD surgery.
恢复成人脊柱畸形(ASD)的矢状面正常排列可改善影像学和临床结果,但包括棒材断裂(RF)在内的假关节形成是一种常见的棘手并发症。本研究的目的是分析在ASD畸形矫正中降低RF发生率的方法。
作者回顾性选取了178例连续的腰椎退行性后凸畸形(LDK)患者(平均年龄70.8岁),这些患者接受了畸形矫正且随访至少2年。患者被分为非RF组(n = 131)和RF组(n = 47)。为预测RF的关键因素,分析了患者因素、影像学参数和手术因素。
RF的总体发生率为26%(47/178例),在椎弓根截骨术(PSO)的患者中发生率为42%(42/100例),在侧方腰椎椎间融合术(LLIF)联合后柱截骨术的患者中发生率为7%(5/67例),在使用钴铬棒的患者中发生率为18%(23/129例)在使用钛合金棒的患者中发生率为49%(24/49例),在采用辅助棒技术置入的患者中发生率为6%(2/36例),在采用双棒技术置入的患者中发生率为32%(45/142例)。两组患者因素方面RF发生率无显著差异。虽然两组术前均存在严重的矢状面失衡,但RF组的腰椎前凸(LL)更呈后凸,骨盆入射角(PI)减去LL(PI - LL)的不匹配更大(p < 0.05)。术后,虽然两组之间LL和PI - LL无显著差异,但RF组的LL和矢状垂直轴矫正更大(p < 0.05)。尽管如此,在末次随访时,除胸腰段交界角外,两组影像学参数无显著差异。至于手术因素,非RF组使用钴铬棒和辅助棒技术的比例显著更高(p < 0.05)。至于矫正方法,PSO比其他矫正方法(包括LLIF)导致更多的RF(p < 0.05)。通过逻辑回归分析,PSO、术前PI - LL不匹配和辅助棒技术是RF的关键因素。
术前矢状面脊柱骨盆排列严重失准,包括术前PI - LL不匹配,是65岁及以上LDK患者发生RF的关键危险因素。为恢复和维持矢状面排列,使用钴铬棒、辅助棒技术或LLIF在ASD手术中被证明可有效降低RF。