Department of Neonatology, Children's Hospital of Soochow University, China.
Medicine (Baltimore). 2021 Feb 19;100(7):e24624. doi: 10.1097/MD.0000000000024624.
Kawasaki Disease (KD) is a self-limiting and acute systemic vasculitis of childhood that leads to coronary artery abnormality in about 25% of untreated cases. KD is extremely rare in neonates. The purpose of this paper is to explore the clinical features and diagnosis and treatment of Neonatal Kawasaki Disease for early identification.
A 24-day-old male with 3 hours fever and a rash was admitted to our hospital.
He had a fever, rash, cracking of lips, lymph node enlargement in the neck, and distal extremity desquamation.
The patient was given intravenous immunoglobulin and aspirin with no complications.
After discharge, the patient was followed up to 1 year old, with good prognosis and no carditis or coronary artery abnormalities.
Neonatal Kawasaki disease is extremely rare, and its clinical manifestation is not typical and easy to be missed. If not treated early, it will potentially give rise to coronary artery aneurysms or expansion, ischemic heart disease, and sudden death. Early diagnosis and treatment are very important.
川崎病（KD）是一种儿童自限性和急性全身性血管炎，未经治疗的病例约有 25%会导致冠状动脉异常。新生儿川崎病极为罕见。本文旨在探讨新生儿川崎病的临床特征、诊断和治疗，以尽早识别。
一名 24 天大的男性，发热 3 小时，伴皮疹，收入我院。
发热、皮疹、唇皲裂、颈部淋巴结肿大、末梢肢端脱皮。
给予患儿丙种球蛋白和阿司匹林治疗，无并发症。
出院后随访至 1 岁，预后良好，无心脏炎或冠状动脉异常。
新生儿川崎病极为罕见，临床表现不典型，易被漏诊。如不早期治疗，可能会导致冠状动脉瘤或扩张、缺血性心脏病和猝死。早期诊断和治疗非常重要。
