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用于外周静脉导管固定的组织粘合剂:一项前瞻性随机对照试验。

Tissue adhesives for peripheral intravenous catheter securement: A prospective randomized controlled pilot trial.

作者信息

Lešnik Amadeus, Gorenjak Mario, Žumer Sandi, Zorčič Valerija, Mišanović Žarko, Majhenič Marko, Podstenšek Anja, Toplak Matevž, Fekonja Urška, Markota Andrej

机构信息

Medical Emergency Department, University Medical Centre Maribor, Ljubljanska 5, Maribor 2000, Slovenia.

Centre for Human Molecular Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, Taborska ulica 8, Maribor 2000, Slovenia.

出版信息

Am J Emerg Med. 2021 Jun;44:128-131. doi: 10.1016/j.ajem.2021.01.088. Epub 2021 Feb 1.

DOI:10.1016/j.ajem.2021.01.088
PMID:33610080
Abstract

BACKGROUND

In some patients securing the peripheral intravenous cannula (PIVC) with a standard adhesive dressing can be difficult because of sweat or other body fluids. The aim of our study was to evaluate the use of tissue adhesives alone as a means to secure PIVCs inserted in the emergency department.

METHODS

We performed a prospective interventional pilot study from November 2019 to May 2020 in a medical emergency department of an urban tertiary hospital. Patients were randomized to two groups: tissue adhesives (TA) or adhesive dressing (AD) group. After randomization we followed them until day 4.

RESULTS

There were no significant differences between TA and AD groups in the rate of unplanned removal of PIVCs in the first 72 h (57.1% vs. 45.8%, p = 0.29), the rate of unplanned removal of PIVCs in the ED (0% vs. 2.1%, p = 1.00), the rate of unplanned removal of PIVC in the first 24 h (42.8% vs. 35.4%, p = 0.52), as well as in the rate of phlebitis (7.1% vs. 14.6%, p = 0.34) and the rate of any blood-stream infection (0% vs. 0%, p = 1.00).

CONCLUSION

We did not observe any significant differences when PIVCs inserted in the emergency department were secured with tissue adhesives alone, compared to standard adhesive dressings. We observed a high rate of unplanned removal of PIVCs, necessitating further research to determine more reliable ways of securing PIVCs.

摘要

背景

在一些患者中,由于出汗或其他体液,使用标准粘性敷料固定外周静脉留置针(PIVC)可能会很困难。我们研究的目的是评估单独使用组织粘合剂作为固定急诊科插入的PIVC的一种方法。

方法

2019年11月至2020年5月,我们在一家城市三级医院的急诊科进行了一项前瞻性干预性试点研究。患者被随机分为两组:组织粘合剂(TA)组或粘性敷料(AD)组。随机分组后,我们对他们进行随访直至第4天。

结果

TA组和AD组在前72小时内PIVC非计划拔除率(57.1%对45.8%,p = 0.29)、急诊科PIVC非计划拔除率(0%对2.1%,p = 1.00)、前24小时内PIVC非计划拔除率(42.8%对35.4%,p = 0.52)、静脉炎发生率(7.1%对14.6%,p = 0.34)以及任何血流感染发生率(0%对0%,p = 1.00)方面均无显著差异。

结论

与标准粘性敷料相比,当单独使用组织粘合剂固定急诊科插入的PIVC时,我们未观察到任何显著差异。我们观察到PIVC非计划拔除率很高,需要进一步研究以确定更可靠的固定PIVC的方法。

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