Northwest Integrated Health, United States of America.
Cordant Health Solutions, United States of America.
J Subst Abuse Treat. 2021 Apr;123:108256. doi: 10.1016/j.jsat.2020.108256. Epub 2020 Dec 18.
Improving access to medications for opioid use disorder (MOUD) is a national priority; however, these efforts commonly focus on the provider. Access to buprenorphine through retail pharmacies and stigma associated with filling prescriptions for MOUD pose additional barriers for patients when embarking on their road to recovery.
This study performed a pre-post retrospective chart review to evaluate the potential positive impact on patient retention when providing buprenorphine at office visits instead of at pharmacies. Study staff reviewed electronic medical records to document patient retention in treatment at 6 months as the primary outcome. The study evaluated as secondary outcomes missed office visits, medication adherence, illicit drug use (that drug testing results identified), and drug-related emergency department (ED) utilization. Study staff documented outcomes for patients given their buprenorphine medication at their office visit (n = 154) compared with randomly selected patients prescribed buprenorphine from the same office-based opioid treatment clinic who had to go to retail pharmacies to fill their prescriptions (n = 154).
Patients receiving buprenorphine at their office visit demonstrated a 52.2% higher retention rate after 6 months compared to the control group (p = .005). Patients were more likely to attend scheduled office visits (p = .046), less likely to test positive for nonprescribed/illicit drugs (p < .001), and less likely to utilize the ED for drug-related reasons (p = .018) when the program alleviated the need to fill buprenorphine prescriptions at retail pharmacies and began to offer the pharmacy services at office visits.
Provision of buprenorphine to patients at their treatment visit was associated with higher patient retention rates and better health outcomes compared with patients who filled their buprenorphine at pharmacies prior to the program's integration of medication provision at patient office visits. Understanding how alleviating barriers to medication access impacts retention in care has meaningful implications for opioid use disorder patients and treatment providers.
改善阿片类药物使用障碍(MOUD)药物的可及性是国家的优先事项;然而,这些努力通常侧重于提供者。通过零售药店获得丁丙诺啡以及与 MOUD 处方相关的耻辱感,给患者在康复之路上带来了额外的障碍。
本研究进行了一项回顾性病例分析,以评估在就诊时而不是在药店提供丁丙诺啡对患者保留率的潜在积极影响。研究人员审查了电子病历,以确定 6 个月时的治疗保留率作为主要结果。该研究还评估了次要结果,包括错过就诊、药物依从性、非法药物使用(药物检测结果确定)和与药物相关的急诊室(ED)就诊。研究人员记录了在就诊时获得丁丙诺啡药物的患者(n=154)与随机选择的来自同一基于办公室的阿片类药物治疗诊所的患者(n=154)的结局,这些患者必须去零售药店取药。
与对照组相比,在就诊时接受丁丙诺啡治疗的患者在 6 个月后的保留率提高了 52.2%(p=0.005)。当该计划缓解了在零售药店填写丁丙诺啡处方的需求,并开始在就诊时提供药房服务时,患者更有可能参加预约就诊(p=0.046),不太可能检测出非处方/非法药物阳性(p<0.001),也不太可能因药物相关原因到 ED 就诊(p=0.018)。
与在该计划整合将药物提供给患者之前在药店取药的患者相比,在就诊时向患者提供丁丙诺啡与更高的保留率和更好的健康结果相关。了解减轻药物获取障碍对保留率的影响对阿片类药物使用障碍患者和治疗提供者具有重要意义。