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短期温水浸泡对动脉僵硬度和中心血流动力学的急性影响。

Acute Effects of Short-Term Warm Water Immersion on Arterial Stiffness and Central Hemodynamics.

作者信息

Sugawara Jun, Tomoto Tsubasa

机构信息

Human Informatics and Interaction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan.

Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, TX, United States.

出版信息

Front Physiol. 2021 Feb 4;12:620201. doi: 10.3389/fphys.2021.620201. eCollection 2021.

Abstract

Warm water immersion (WWI) has a potentially favorable effect on vascular health. However, the effects of short-term WWI on vascular function and central hemodynamics remain unclear. The present study aimed to determine the acute effects of short-term WWI on arterial stiffness and central hemodynamics in healthy men. Ten healthy men (27-57 years, 44 ± 12 years of mean age) underwent 5-min WWI (40-41°C) at the heart level. Systemic hemodynamics and tympanic temperature were monitored during WWI. Furthermore, pulse wave velocity (PWV) and aortic hemodynamics were measured before and 10 min after WWI. Cardiac output (CO) (via the Modelflow method) increased ( = 0.037), whereas tympanic temperature did not change ( = 0.879) during WWI. After 5-min WWI, heart rate (HR) and brachial diastolic blood pressure (BP) were significantly decreased. Aortic and leg PWV were decreased by 7.5 and 3.1%, respectively ( = 0.006 and = 0.040). Femoral arterial blood flow was increased by 45.9% ( = 0.002), and leg vascular resistance was decreased by 29.1% ( < 0.001). Regarding central hemodynamic variables (estimated by general transfer function), aortic BP and augmentation index (AIx) did not change significantly, but the subendocardial viability ratio (SEVR), an index of coronary perfusion, was increased ( = 0.049). Our results indicate that a short-term WWI acutely improves aortic and peripheral arterial stiffness and coronary perfusion. Further studies to determine the interaction between the residual effect of a single bout of short-term WWI and chronic change (e.g., adaptation) in arterial stiffness and central hemodynamics are needed.

摘要

温水浸泡(WWI)对血管健康可能具有有益作用。然而,短期WWI对血管功能和中心血流动力学的影响仍不清楚。本研究旨在确定短期WWI对健康男性动脉僵硬度和中心血流动力学的急性影响。10名健康男性(年龄27 - 57岁,平均年龄44±12岁)在心脏水平接受5分钟的WWI(40 - 41°C)。在WWI期间监测全身血流动力学和鼓膜温度。此外,在WWI前和WWI后10分钟测量脉搏波速度(PWV)和主动脉血流动力学。心输出量(CO)(通过模型流量法)增加(P = 0.037),而在WWI期间鼓膜温度没有变化(P = 0.879)。5分钟的WWI后,心率(HR)和肱动脉舒张压(BP)显著降低。主动脉和腿部PWV分别降低了7.5%和3.1%(P = 0.006和P = 0.040)。股动脉血流量增加了45.9%(P = 0.002),腿部血管阻力降低了29.1%(P < 0.001)。关于中心血流动力学变量(通过通用传递函数估计),主动脉血压和增强指数(AIx)没有显著变化,但作为冠状动脉灌注指标的心内膜下存活比率(SEVR)增加了(P = 0.049)。我们的结果表明,短期WWI可急性改善主动脉和外周动脉僵硬度以及冠状动脉灌注。需要进一步研究以确定单次短期WWI的残余效应与动脉僵硬度和中心血流动力学的慢性变化(例如适应性)之间的相互作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5493/7890244/2c36fab30829/fphys-12-620201-g001.jpg

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