肠易激综合征与月经周期
Irritable Bowel Syndrome and the Menstrual Cycle.
作者信息
Pati Girish K, Kar Chinmayee, Narayan Jimmy, Uthansingh Kanishka, Behera Manas, Sahu Manoj K, Mishra Debakanta, Singh Ayaskanta
机构信息
Gastroenterology, Institute of Medical Sciences and SUM Hospital, Bhubaneswar, IND.
Obstetrics and Gynecology, SUM Ultimate Medicare, Siksha 'O' Anusandhan University, Bhubaneswar, IND.
出版信息
Cureus. 2021 Jan 14;13(1):e12692. doi: 10.7759/cureus.12692.
INTRODUCTION
Irritable bowel syndrome (IBS) is a common gastrointestinal (GI) disorder. Female patients with bowel disease commonly report worsening of symptoms in the menstrual cycle. However, there is a paucity of data regarding IBS presentations' variation during different phases of the menstrual cycle. The current study aimed to evaluate the same in female IBS patients.
MATERIALS AND METHODS
Consecutive premenopausal female patients with the diagnosis of IBS attending the outdoor (OPD) of Department of Gastroenterology and Gynaecology; IMS and SUM Hospital, Bhubaneswar, Odisha from June 2019 to December 2019 were included in the study and evaluated by a set of questionnaires regarding various presentations during all the three phases of the menstrual cycle.
RESULTS
Consecutive 102 cases with the diagnosis of IBS were included in the study and evaluated. The mean age of presentation was in mid-30s. Most of the subjects suffered from IBS mixed (IBS-M) type. More patients significantly suffered from constipation (27.27%) during the luteal phase of their menstrual cycles than the menstrual period of their cycles (p - 0.009). More than 50% of all the cases suffered from abdominal bloating during all phases of the menstrual cycle, which was quite disturbing and affected the quality of life. These IBS patients were more symptomatic with more significant limitation of daily activities, suffered from low quality of life, and obtained physician consultation during the menstrual phase as compared to other cycle stages.
CONCLUSION
Premenopausal female patients with IBS become much more symptomatic during the menstrual phase of the cycle than other stages of the cycle.
引言
肠易激综合征(IBS)是一种常见的胃肠道疾病。患有肠道疾病的女性患者通常报告在月经周期中症状会加重。然而,关于肠易激综合征在月经周期不同阶段表现变化的数据却很匮乏。本研究旨在评估女性肠易激综合征患者的这一情况。
材料与方法
纳入2019年6月至2019年12月期间在印度奥里萨邦布巴内斯瓦尔市IMS和SUM医院胃肠病学与妇科门诊就诊的连续绝经前确诊为肠易激综合征的女性患者,并通过一套问卷对她们在月经周期所有三个阶段的各种表现进行评估。
结果
本研究纳入并评估了连续102例确诊为肠易激综合征的病例。发病的平均年龄在35岁左右。大多数受试者患有混合型肠易激综合征(IBS-M)。与月经周期的月经期相比,更多患者在月经周期的黄体期明显患有便秘(27.27%)(p = 0.009)。超过50%的所有病例在月经周期的所有阶段都有腹胀,这相当令人困扰并影响生活质量。与其他周期阶段相比,这些肠易激综合征患者在月经期症状更明显,日常活动受限更显著,生活质量较低,且会寻求医生咨询。
结论
绝经前患有肠易激综合征的女性患者在月经周期的月经期比其他阶段症状更明显。
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