Suppr超能文献

中风继发精神病的治疗困境

Dilemma of Treating Psychosis Secondary to Stroke.

作者信息

Agrawal Ruchita, Verma Shikha, Vatsalya Vatsalya, Halappanavar Monica, Oraka Kosisochukwu

机构信息

Psychiatry, Seven Counties Services, Louisville, USA.

Psychiatry and Behavioral Health, Rosalind Franklin University, North Chicago, USA.

出版信息

Cureus. 2021 Jan 18;13(1):e12763. doi: 10.7759/cureus.12763.

Abstract

Post-stroke psychosis is prevalent and disabling with increased mortality risk. Treatment for post-stroke psychosis is limited in this staggering medical concern. The most commonly used medications are antipsychotics, however, the risk for stroke increases further with the use of antipsychotics. Furthermore, interventional clinical studies have not been carried out to test the efficacy and safety of antipsychotics in the management of post-stroke psychosis. We present a case of post-stroke psychosis to highlight the risks faced by these patients in terms of daily function and safety concerns and the challenges encountered in treatment due to poor response to the conventional antipsychotics; and so calling attention to early diagnosis and improved treatment options. More clinical investigations are needed to address the pathology associated with the clinical presentation and exploring the pharmacotherapies to improve efficacy and safety of treatment for post-stroke psychosis.

摘要

中风后精神病很常见且会导致残疾,同时死亡风险增加。在这个令人震惊的医学问题中,中风后精神病的治疗方法有限。最常用的药物是抗精神病药,然而,使用抗精神病药会进一步增加中风风险。此外,尚未开展干预性临床研究来测试抗精神病药在治疗中风后精神病方面的疗效和安全性。我们报告一例中风后精神病病例,以强调这些患者在日常功能和安全方面面临的风险,以及由于对传统抗精神病药反应不佳在治疗中遇到的挑战;从而呼吁关注早期诊断和改进治疗方案。需要更多的临床研究来解决与临床表现相关的病理问题,并探索提高中风后精神病治疗疗效和安全性的药物疗法。

相似文献

1
Dilemma of Treating Psychosis Secondary to Stroke.
Cureus. 2021 Jan 18;13(1):e12763. doi: 10.7759/cureus.12763.
2
Impact of Current Antipsychotic Medications on Comparative Mortality and Adverse Events in People With Parkinson Disease Psychosis.
J Am Med Dir Assoc. 2015 Oct 1;16(10):898.e1-7. doi: 10.1016/j.jamda.2015.06.021. Epub 2015 Aug 1.
3
Poststroke psychosis: a systematic review.
J Neurol Neurosurg Psychiatry. 2018 Aug;89(8):879-885. doi: 10.1136/jnnp-2017-317327. Epub 2018 Jan 13.
4
Psychosis secondary to COVID-19 in pediatric sickle cell disease.
Clin Case Rep. 2024 Feb 13;12(2):e8536. doi: 10.1002/ccr3.8536. eCollection 2024 Feb.
6
Myxedema Psychosis: Neuropsychiatric Manifestations and Rhabdomyolysis Unmasking Hypothyroidism.
Case Rep Psychiatry. 2020 Jun 22;2020:7801953. doi: 10.1155/2020/7801953. eCollection 2020.
9
Treatment for amphetamine psychosis.
Cochrane Database Syst Rev. 2008 Oct 8(4):CD003026. doi: 10.1002/14651858.CD003026.pub2.
10
Long-acting injectable antipsychotics in the elderly: guidelines for effective use.
Drugs Aging. 2003;20(15):1099-110. doi: 10.2165/00002512-200320150-00003.

本文引用的文献

1
Organic psychosis: The pathobiology and treatment of delusions.
CNS Neurosci Ther. 2018 Jul;24(7):598-603. doi: 10.1111/cns.12973. Epub 2018 May 15.
2
Poststroke psychosis: a systematic review.
J Neurol Neurosurg Psychiatry. 2018 Aug;89(8):879-885. doi: 10.1136/jnnp-2017-317327. Epub 2018 Jan 13.
4
Post Stroke Psychosis Following Lesions in Basal Ganglion.
J Clin Diagn Res. 2017 May;11(5):VD01-VD02. doi: 10.7860/JCDR/2017/24142.9790. Epub 2017 May 1.
5
Delusions and the Right Hemisphere: A Review of the Case for the Right Hemisphere as a Mediator of Reality-Based Belief.
J Neuropsychiatry Clin Neurosci. 2017 Summer;29(3):225-235. doi: 10.1176/appi.neuropsych.16060118. Epub 2017 Mar 28.
6
Psychosis following a stroke to the cerebellum and midbrain: a case report.
Cerebellum Ataxias. 2015 Dec 9;2:17. doi: 10.1186/s40673-015-0037-8. eCollection 2015.
7
Effective treatment with clozapine and valproate for refractory schizophrenia-like psychosis after cerebellar hemorrhage.
Clin Neuropharmacol. 2011 May-Jun;34(3):131-2. doi: 10.1097/WNF.0b013e31821f4d91.
8
Clinical and imaging features of Othello's syndrome.
Eur J Neurol. 2012 Jan;19(1):38-46. doi: 10.1111/j.1468-1331.2011.03412.x. Epub 2011 Apr 25.
9
Mortality associated with incident mental health disorders after stroke.
Aust N Z J Psychiatry. 2007 Mar;41(3):274-81. doi: 10.1080/00048670601172772.
10
Preventing stroke: saving lives around the world.
Lancet Neurol. 2007 Feb;6(2):182-7. doi: 10.1016/S1474-4422(07)70031-5.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验