Acar Damla Erginturk, Acar Ugur, Tunay Zuhal Ozen, Arman Aysegul, Barak Anil
Minister of Health Ankara City Hospital, Ankara 06800, Turkey.
Selcuk University Faculty of Medicine, Konya 42250, Turkey.
Int J Ophthalmol. 2021 Feb 18;14(2):277-282. doi: 10.18240/ijo.2021.02.15. eCollection 2021.
To investigate the effects of diode laser treatment on ocular biometric parameters in premature infants with retinopathy of prematurity (ROP).
Premature infants who received diode laser treatment for ROP (=68) and premature infants with spontaneous regressed ROP without treatment (=50) were performed longitudinal ocular biometric measurements including anterior chamber depth, lens thickness and axial length as follows: 1d prior to laser treatment, and 3, 6, 9, and 12mo after the laser treatment.
The mean birth weight, gestational age and initial examination time values were 936.53±302.07 g, 26.66±2.42wk, 36.26±2.73wk in the treatment group and 959.78±260.08 g, 27.28±2.10wk, 36.56±2.54wk in the control group. There was no statistically significant difference in these demographic characteristics of the groups. Anterior chamber depth, lens thickness and axial length demonstrated statistically significant linear increases during the study period in the two groups (<0.001 for each). There were no statistically significant differences between the two groups in terms of anterior chamber depth after laser treatment. Measurements of the lens thickness at 9 and 12 months (9 month 3.70±0.22 3.60±0.21 mm, =0.017; 12 month 3.81±0.21 3.69±0.22 mm, =0.002) and the axial length at 12 month (19.35±0.79 19.13±0.54 mm, =0.031) after laser treatment were statistically higher in the treatment group.
Diode laser retinal photocoagulation treatment in premature infants seems to increase the lens thickness and axial length.
探讨二极管激光治疗对早产儿视网膜病变（ROP）患儿眼部生物测量参数的影响。
对接受二极管激光治疗ROP的早产儿（=68例）和未经治疗而ROP自然消退的早产儿（=50例）进行眼部生物测量参数的纵向测量，包括前房深度、晶状体厚度和眼轴长度，测量时间如下：激光治疗前1天，以及激光治疗后3、6、9和12个月。
治疗组的平均出生体重、胎龄和初次检查时间值分别为936.53±302.07g、26.66±2.42周、36.26±2.73周，对照组分别为959.78±260.08g、27.28±2.10周、36.56±2.54周。两组的这些人口统计学特征无统计学显著差异。在研究期间，两组的前房深度、晶状体厚度和眼轴长度均呈统计学显著的线性增加（每项均<0.001）。激光治疗后两组在前房深度方面无统计学显著差异。治疗组激光治疗后9个月和12个月的晶状体厚度测量值（9个月 3.70±0.22对3.60±0.21mm，P=0.017；12个月 3.81±0.21对3.69±0.22mm，P=0.002）以及12个月的眼轴长度测量值（19.35±0.79对19.13±0.54mm，P=0.031）在统计学上更高。
早产儿二极管激光视网膜光凝治疗似乎会增加晶状体厚度和眼轴长度。
