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一名年轻男性的枕部纤维性脱发:病例报告

Occipital Fibrosing Alopecia in a Young Male: A Case Report.

作者信息

Doche Isabella, Rebeis Marina, Valente Neusa, Rivitti-Machado Maria Cecília

机构信息

Department of Dermatology, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.

出版信息

Skin Appendage Disord. 2021 Jan;7(1):71-74. doi: 10.1159/000512034. Epub 2020 Dec 17.

Abstract

INTRODUCTION

Lichen planopilaris (LPP) is a primary lymphocytic cicatricial alopecia with 3 recognized clinical variants. Lately, LPP clinical spectrum has expanded with new and overlapping clinical variants. First considered as a subtype of LPP affecting postmenopausal women, the increasing worldwide incidence of FFA including atypical lesions in young female and male suggests a different pathomechanism for this disease. Although LPP-spectrum disorders may share similar histopathological findings, clinical features and prognosis are different.

CASE REPORT

A 26-year-old Caucasian male presented with occipital scarring alopecia and pruritus for the last 6 months. The patient had been treated for an associated androgenetic alopecia and superficial recurrent scalp folliculitis over the vertex scalp for the last 5 years. Trichoscopy of the occipital scalp showed mild diffuse erythema, moderate peripilar scaling, and absence of follicular openings, suggestive of a scarring process. The patient underwent an occipital scalp biopsy that confirmed the diagnosis of a LPP-spectrum disorder.

DISCUSSION/CONCLUSION: Both LPP and FFA mostly affect the anterior-mid scalp of females. However, recent reports on FFA also in premenopausal women and men should make physicians aware of atypical features of this disease and unusual clinical presentation.

摘要

引言

扁平苔藓样毛发角化病(LPP)是一种原发性淋巴细胞性瘢痕性脱发,有3种公认的临床变体。近来,LPP的临床谱随着新的和重叠的临床变体而扩大。FFA最初被认为是LPP的一种亚型,影响绝经后女性,但全球范围内FFA发病率上升,包括年轻女性和男性中的非典型病变,提示该病有不同的发病机制。尽管LPP谱系疾病可能有相似的组织病理学表现,但临床特征和预后不同。

病例报告

一名26岁的白种男性在过去6个月出现枕部瘢痕性脱发和瘙痒。该患者在过去5年中一直在治疗头顶头皮的雄激素性脱发和浅表复发性头皮毛囊炎。枕部头皮的毛发镜检查显示轻度弥漫性红斑、中度毛囊周围脱屑,且无毛囊开口,提示有瘢痕形成过程。患者接受了枕部头皮活检,确诊为LPP谱系疾病。

讨论/结论:LPP和FFA大多影响女性的前中头皮。然而,最近关于绝经前女性和男性中FFA的报道应使医生意识到该病的非典型特征和不寻常的临床表现。

相似文献

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Occipital Fibrosing Alopecia in a Young Male: A Case Report.一名年轻男性的枕部纤维性脱发:病例报告
Skin Appendage Disord. 2021 Jan;7(1):71-74. doi: 10.1159/000512034. Epub 2020 Dec 17.

本文引用的文献

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Frontal fibrosing alopecia among men: A clinicopathologic study of 7 cases.男性额部纤维性脱发:7 例临床病理研究。
J Am Acad Dermatol. 2017 Oct;77(4):683-690.e2. doi: 10.1016/j.jaad.2017.05.045. Epub 2017 Jul 14.
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Update on lichen planus and its clinical variants.扁平苔藓及其临床变体的最新进展。
Int J Womens Dermatol. 2015 Sep 16;1(3):140-149. doi: 10.1016/j.ijwd.2015.04.001. eCollection 2015 Aug.

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