Weston Gillian, Payette Michael
University of Connecticut School of Medicine, Farmington, CT.
Department of Dermatology, University of Connecticut Health Center, Farmington, CT.
Int J Womens Dermatol. 2015 Sep 16;1(3):140-149. doi: 10.1016/j.ijwd.2015.04.001. eCollection 2015 Aug.
Lichen planus (LP) is an inflammatory skin condition with characteristic clinical and histopathological findings. Classic LP typically presents as pruritic, polygonal, violaceous flat-topped papules and plaques; many variants in morphology and location also exist, including oral, nail, linear, annular, atrophic, hypertrophic, inverse, eruptive, bullous, ulcerative, lichen planus pigmentosus, lichen planopilaris, vulvovaginal, actinic, lichen planus-lupus erythematosus overlap syndrome, and lichen planus pemphigoides. Clinical presentation of the rarer variant lesions may be largely dissimilar to classic LP and therefore difficult to diagnose based solely on clinical examination. However, histopathological examination of LP and LP-variant lesions reveal similar features, aiding in the proper diagnosis of the disease. Management of LP and LP variants aims to control symptoms and to decrease time from onset to resolution; it often involves topical corticosteroids, but varies depending on the severity and location of the lesion. The literature contains an array of reports on the variations in presentation and successful management of LP and its variants. A familiarity with LP and its variants is important in achieving timely recognition and management of the disease.
扁平苔藓（LP）是一种具有特征性临床和组织病理学表现的炎症性皮肤病。典型的LP通常表现为瘙痒性、多边形、紫红色扁平丘疹和斑块；在形态和部位上也存在许多变体，包括口腔、指甲、线状、环状、萎缩性、肥厚性、反向性、发疹性、大疱性、溃疡性、色素性扁平苔藓、扁平毛发苔藓、外阴阴道型、光化性、扁平苔藓 - 红斑狼疮重叠综合征以及大疱性扁平苔藓。较罕见的变体病变的临床表现可能与典型LP大不相同，因此仅基于临床检查很难诊断。然而，LP及其变体病变的组织病理学检查显示出相似的特征，有助于对该疾病进行正确诊断。LP及其变体的治疗旨在控制症状并缩短从发病到缓解的时间；通常涉及外用糖皮质激素，但会根据病变的严重程度和部位而有所不同。文献中有一系列关于LP及其变体的表现差异和成功治疗的报道。熟悉LP及其变体对于及时识别和治疗该疾病很重要。
